HPS1-AS1

Summary

HPS1-AS1 (HPS1 antisense RNA 1, HGNC:56166) is a long non-coding RNA gene on chromosome 10q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56166
Approved symbol	HPS1-AS1
Name	HPS1 antisense RNA 1
Location	10q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000287261
Ensembl biotype	lncRNA
Entrez	101927278
RNAcentral	URS0000A772B3 — lncRNA, 979 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 30 — 30 lncRNA

ENST00000660697, ENST00000689913, ENST00000692432, ENST00000701160, ENST00000789499, ENST00000789500, ENST00000789501, ENST00000789502, ENST00000789503, ENST00000789504, ENST00000789505, ENST00000789506, ENST00000789507, ENST00000789508, ENST00000789509, ENST00000789510, ENST00000789511, ENST00000789512, ENST00000789513, ENST00000789514, ENST00000789515, ENST00000789516, ENST00000789517, ENST00000789518, ENST00000789519, ENST00000789520, ENST00000789521, ENST00000789522, ENST00000789523, ENST00000789524

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000660697 — 3 exons

Exon	Start	End
ENSE00003878870	98453199	98453810
ENSE00003882525	98449347	98449381
ENSE00004168836	98446281	98446761

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 94.91.

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	94.91	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.55	gold quality
left testis	UBERON:0004533	82.96	gold quality
right testis	UBERON:0004534	82.90	gold quality
testis	UBERON:0000473	80.64	gold quality
epithelial cell of pancreas	CL:0000083	72.47	gold quality
bone marrow cell	CL:0002092	71.03	silver quality
kidney epithelium	UBERON:0004819	70.77	gold quality
sural nerve	UBERON:0015488	70.04	gold quality
tendon of biceps brachii	UBERON:0008188	65.57	gold quality
monocyte	CL:0000576	65.54	gold quality
cortical plate	UBERON:0005343	64.31	gold quality
superficial temporal artery	UBERON:0001614	64.07	gold quality
prefrontal cortex	UBERON:0000451	63.65	gold quality
ventricular zone	UBERON:0003053	63.31	gold quality
adult organism	UBERON:0007023	62.61	gold quality
left adrenal gland	UBERON:0001234	62.40	gold quality
left adrenal gland cortex	UBERON:0035825	62.25	gold quality
bone marrow	UBERON:0002371	62.17	gold quality
granulocyte	CL:0000094	62.09	gold quality
islet of Langerhans	UBERON:0000006	61.86	gold quality
ganglionic eminence	UBERON:0004023	61.74	gold quality
tendon	UBERON:0000043	61.42	gold quality
adrenal cortex	UBERON:0001235	61.25	gold quality
right adrenal gland	UBERON:0001233	61.12	gold quality
tibial artery	UBERON:0007610	60.96	gold quality
popliteal artery	UBERON:0002250	60.92	gold quality
putamen	UBERON:0001874	60.82	gold quality
adrenal gland	UBERON:0002369	60.65	gold quality
nucleus accumbens	UBERON:0001882	60.64	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.