HPYR1

Summary

HPYR1 (Helicobacter pylori responsive 1, HGNC:16071) is a long non-coding RNA gene on chromosome 8q24.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16071
Approved symbol	HPYR1
Name	Helicobacter pylori responsive 1
Location	8q24.22
Locus type	RNA, long non-coding
Status	Approved
Aliases	HPRG1, NCRNA00027, LINC00027
Ensembl gene	ENSG00000253521
Ensembl biotype	lncRNA
Entrez	93668
RNAcentral	URS0000615ADA — lncRNA, 982 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000520457, ENST00000648355

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000520457 — 1 exons

Exon	Start	End
ENSE00002134497	132560498	132561479

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 75.83.

Top tissues by expression

190 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.83	gold quality
right uterine tube	UBERON:0001302	62.54	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	60.08	gold quality
cortical plate	UBERON:0005343	60.01	silver quality
ventricular zone	UBERON:0003053	58.58	gold quality
ganglionic eminence	UBERON:0004023	55.76	silver quality
prefrontal cortex	UBERON:0000451	54.65	gold quality
skin of hip	UBERON:0001554	54.48	silver quality
right frontal lobe	UBERON:0002810	52.84	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.64	gold quality
nucleus accumbens	UBERON:0001882	51.69	gold quality
caudate nucleus	UBERON:0001873	51.15	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.97	gold quality
upper leg skin	UBERON:0004262	50.64	silver quality
frontal cortex	UBERON:0001870	50.60	gold quality
calcaneal tendon	UBERON:0003701	50.28	silver quality
neocortex	UBERON:0001950	50.22	gold quality
putamen	UBERON:0001874	49.68	gold quality
anterior cingulate cortex	UBERON:0009835	49.51	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.31	gold quality
islet of Langerhans	UBERON:0000006	49.08	silver quality
blood	UBERON:0000178	48.33	silver quality
cerebral cortex	UBERON:0000956	48.30	gold quality
forebrain	UBERON:0001890	47.62	gold quality
cerebellar hemisphere	UBERON:0002245	47.34	gold quality
brain	UBERON:0000955	47.13	gold quality
right hemisphere of cerebellum	UBERON:0014890	46.84	gold quality
primary visual cortex	UBERON:0002436	46.83	gold quality
monocyte	CL:0000576	46.62	silver quality
caecum	UBERON:0001153	46.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.