HRG-AS1

Summary

HRG-AS1 (HRG and FETUB antisense RNA 1, HGNC:55915) is a long non-coding RNA gene on chromosome 3q27.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55915
Approved symbol	HRG-AS1
Name	HRG and FETUB antisense RNA 1
Location	3q27.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-573D15.8
Ensembl gene	ENSG00000197099
Ensembl biotype	lncRNA
Entrez	105374258
RNAcentral	URS00026A2207 — lncRNA, 346 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 59 — 59 lncRNA

ENST00000354642, ENST00000428501, ENST00000455926, ENST00000596329, ENST00000596632, ENST00000599314, ENST00000608173, ENST00000609652, ENST00000609726, ENST00000625303, ENST00000625386, ENST00000625690, ENST00000625710, ENST00000625741, ENST00000625826, ENST00000625839, ENST00000625869, ENST00000625877, ENST00000626006, ENST00000626151, ENST00000626306, ENST00000626520, ENST00000626586, ENST00000626633, ENST00000626649, ENST00000626845, ENST00000626978, ENST00000627015, ENST00000627268, ENST00000627469, ENST00000627551, ENST00000627830, ENST00000627919, ENST00000628020, ENST00000628190, ENST00000628253, ENST00000628291, ENST00000628505, ENST00000628601, ENST00000628728, ENST00000628831, ENST00000628858, ENST00000628928, ENST00000629106, ENST00000629126, ENST00000629201, ENST00000629451, ENST00000629734, ENST00000629954, ENST00000630178, ENST00000630315, ENST00000630331, ENST00000630726, ENST00000630864, ENST00000631299, ENST00000804467, ENST00000804468, ENST00000840331, ENST00000840332

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000354642 — 7 exons

Exon	Start	End
ENSE00001430417	186745730	186745849
ENSE00001636623	186746077	186746130
ENSE00001648517	186743703	186743841
ENSE00001698041	186736539	186736650
ENSE00001775524	186734713	186734834
ENSE00003054436	186718467	186718569
ENSE00003765181	186714448	186714539

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 91.49.

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	91.49	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.02	gold quality
liver	UBERON:0002107	81.35	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.13	gold quality
colonic epithelium	UBERON:0000397	78.72	gold quality
metanephros cortex	UBERON:0010533	76.65	gold quality
adult mammalian kidney	UBERON:0000082	76.59	gold quality
right testis	UBERON:0004534	72.43	gold quality
monocyte	CL:0000576	71.88	gold quality
left testis	UBERON:0004533	71.85	gold quality
right uterine tube	UBERON:0001302	71.18	gold quality
leukocyte	CL:0000738	71.10	gold quality
testis	UBERON:0000473	70.94	gold quality
sural nerve	UBERON:0015488	70.25	gold quality
cortex of kidney	UBERON:0001225	69.06	gold quality
lower esophagus mucosa	UBERON:0035834	68.40	gold quality
kidney	UBERON:0002113	68.35	gold quality
ganglionic eminence	UBERON:0004023	66.19	gold quality
adrenal tissue	UBERON:0018303	66.16	gold quality
granulocyte	CL:0000094	65.98	gold quality
metanephros	UBERON:0000081	65.96	gold quality
bone marrow cell	CL:0002092	65.19	silver quality
cortical plate	UBERON:0005343	63.96	gold quality
rectum	UBERON:0001052	63.25	gold quality
blood	UBERON:0000178	63.04	gold quality
left coronary artery	UBERON:0001626	61.58	gold quality
esophagus mucosa	UBERON:0002469	61.22	gold quality
right coronary artery	UBERON:0001625	60.90	gold quality
vermiform appendix	UBERON:0001154	60.59	gold quality
ascending aorta	UBERON:0001496	60.55	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	40.42
E-ANND-3	yes	7.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.