HSD17B1-AS1

Summary

HSD17B1-AS1 (HSD17B1 antisense RNA 1, HGNC:55314) is a long non-coding RNA gene on chromosome 17q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55314
Approved symbol	HSD17B1-AS1
Name	HSD17B1 antisense RNA 1
Location	17q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266962
Ensembl biotype	lncRNA
Entrez	108783654
RNAcentral	URS00025F8363 — lncRNA, 2411 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000590513, ENST00000803215, ENST00000803216

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000590513 — 1 exons

Exon	Start	End
ENSE00003985133	42552431	42554841

Expression profiles

Bgee: expression breadth ubiquitous, 207 present calls, max score 94.86.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 12.5012 / max 60.6370, expressed in 1786 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
166168	12.5012	1786

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
pancreatic ductal cell	CL:0002079	94.86	gold quality
left ventricle myocardium	UBERON:0006566	84.97	gold quality
cardiac muscle of right atrium	UBERON:0003379	84.95	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.79	gold quality
apex of heart	UBERON:0002098	83.48	gold quality
tendon of biceps brachii	UBERON:0008188	82.89	silver quality
prefrontal cortex	UBERON:0000451	82.85	gold quality
gingival epithelium	UBERON:0001949	82.56	gold quality
right frontal lobe	UBERON:0002810	82.25	gold quality
kidney epithelium	UBERON:0004819	82.10	gold quality
right hemisphere of cerebellum	UBERON:0014890	81.65	gold quality
mucosa of transverse colon	UBERON:0004991	81.48	gold quality
ileal mucosa	UBERON:0000331	81.27	silver quality
cerebellar hemisphere	UBERON:0002245	81.01	gold quality
cerebellar cortex	UBERON:0002129	80.99	gold quality
frontal cortex	UBERON:0001870	80.88	gold quality
anterior cingulate cortex	UBERON:0009835	80.81	gold quality
cerebellum	UBERON:0002037	80.78	gold quality
heart left ventricle	UBERON:0002084	80.62	gold quality
neocortex	UBERON:0001950	80.58	gold quality
right lobe of liver	UBERON:0001114	80.39	gold quality
cardiac ventricle	UBERON:0002082	80.36	gold quality
Brodmann (1909) area 9	UBERON:0013540	80.28	gold quality
gingiva	UBERON:0001828	79.75	gold quality
putamen	UBERON:0001874	79.67	gold quality
body of stomach	UBERON:0001161	79.65	gold quality
amygdala	UBERON:0001876	79.50	gold quality
lower esophagus muscularis layer	UBERON:0035833	79.45	gold quality
lower esophagus	UBERON:0013473	79.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	79.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.