HSD17B2-AS1

Summary

HSD17B2-AS1 (HSD17B2 antisense RNA 1, HGNC:56281) is a long non-coding RNA gene on chromosome 16q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56281
Approved symbol	HSD17B2-AS1
Name	HSD17B2 antisense RNA 1
Location	16q23.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-510J16.5, AS-HSD17beta2
Ensembl gene	ENSG00000261235
Ensembl biotype	lncRNA
Entrez	105371363
RNAcentral	URS0002A2300B — lncRNA, 872 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000561826, ENST00000567021, ENST00000719932, ENST00000719933, ENST00000719934

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561826 — 3 exons

Exon	Start	End
ENSE00002589133	82063093	82063222
ENSE00002599517	82044336	82044605
ENSE00002611903	82052293	82052458

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 90.07.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.07	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.82	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	68.58	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.25	gold quality
liver	UBERON:0002107	67.69	gold quality
placenta	UBERON:0001987	66.99	gold quality
colonic epithelium	UBERON:0000397	64.04	silver quality
ventricular zone	UBERON:0003053	63.33	gold quality
right lobe of liver	UBERON:0001114	63.21	gold quality
fundus of stomach	UBERON:0001160	61.44	gold quality
lymph node	UBERON:0000029	61.03	gold quality
metanephros cortex	UBERON:0010533	60.07	gold quality
lower esophagus mucosa	UBERON:0035834	59.83	gold quality
urinary bladder	UBERON:0001255	59.63	gold quality
body of stomach	UBERON:0001161	59.03	gold quality
stomach	UBERON:0000945	58.77	gold quality
minor salivary gland	UBERON:0001830	58.34	gold quality
saliva-secreting gland	UBERON:0001044	58.10	gold quality
cortex of kidney	UBERON:0001225	57.67	gold quality
adult mammalian kidney	UBERON:0000082	57.28	gold quality
kidney	UBERON:0002113	57.10	gold quality
mucosa of transverse colon	UBERON:0004991	57.02	gold quality
duodenum	UBERON:0002114	56.69	gold quality
tonsil	UBERON:0002372	55.94	gold quality
gall bladder	UBERON:0002110	55.73	gold quality
esophagus mucosa	UBERON:0002469	54.86	gold quality
esophagus	UBERON:0001043	54.27	gold quality
monocyte	CL:0000576	53.79	gold quality
islet of Langerhans	UBERON:0000006	52.98	gold quality
leukocyte	CL:0000738	52.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.51

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.