HSPA2-AS1

Summary

HSPA2-AS1 (HSPA2 and ZBTB1 antisense RNA 1, HGNC:55433) is a long non-coding RNA gene on chromosome 14q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55433
Approved symbol	HSPA2-AS1
Name	HSPA2 and ZBTB1 antisense RNA 1
Location	14q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259116
Ensembl biotype	lncRNA
Entrez	102723809
RNAcentral	URS000075A2E9 — lncRNA, 561 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000554918, ENST00000648003, ENST00000846147, ENST00000846148, ENST00000846149

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000554918 — 4 exons

Exon	Start	End
ENSE00002433699	64518357	64518538
ENSE00002500784	64514154	64514381
ENSE00002513073	64532474	64532569
ENSE00002515429	64540317	64540368

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 79.68.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0142 / max 2.7065, expressed in 6 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
143636	0.0142	6

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.68	gold quality
left testis	UBERON:0004533	76.84	gold quality
sperm	CL:0000019	76.78	gold quality
right testis	UBERON:0004534	75.26	gold quality
testis	UBERON:0000473	75.07	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.52	gold quality
bone marrow cell	CL:0002092	73.58	gold quality
pancreatic ductal cell	CL:0002079	72.26	silver quality
monocyte	CL:0000576	71.36	gold quality
stromal cell of endometrium	CL:0002255	69.61	gold quality
body of pancreas	UBERON:0001150	68.84	gold quality
colonic epithelium	UBERON:0000397	68.53	gold quality
calcaneal tendon	UBERON:0003701	68.34	gold quality
right coronary artery	UBERON:0001625	68.33	gold quality
skin of abdomen	UBERON:0001416	67.53	gold quality
right ovary	UBERON:0002118	66.63	gold quality
skin of leg	UBERON:0001511	66.59	gold quality
endocervix	UBERON:0000458	66.42	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.28	gold quality
tendon	UBERON:0000043	66.17	gold quality
descending thoracic aorta	UBERON:0002345	66.15	gold quality
right lobe of thyroid gland	UBERON:0001119	66.03	gold quality
tibial nerve	UBERON:0001323	65.99	gold quality
cortical plate	UBERON:0005343	65.97	gold quality
body of uterus	UBERON:0009853	65.90	gold quality
left ovary	UBERON:0002119	65.43	gold quality
minor salivary gland	UBERON:0001830	65.31	gold quality
ganglionic eminence	UBERON:0004023	65.21	gold quality
rectum	UBERON:0001052	64.72	gold quality
zone of skin	UBERON:0000014	64.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.