HSPB8-AS1

Summary

HSPB8-AS1 (HSPB8 antisense RNA 1, HGNC:58274) is a long non-coding RNA gene on chromosome 12q24.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58274
Approved symbol	HSPB8-AS1
Name	HSPB8 antisense RNA 1
Location	12q24.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256609
Ensembl biotype	lncRNA
Entrez	107984440
RNAcentral	URS0002A41869 — lncRNA, 1422 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000535921

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000535921 — 2 exons

Exon	Start	End
ENSE00004108733	119181167	119182202
ENSE00004108734	119182874	119183259

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 95.93.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.93	silver quality
colonic epithelium	UBERON:0000397	87.00	gold quality
corpus callosum	UBERON:0002336	85.89	gold quality
skeletal muscle tissue	UBERON:0001134	77.78	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.43	gold quality
lower esophagus mucosa	UBERON:0035834	71.79	gold quality
mucosa of stomach	UBERON:0001199	71.12	gold quality
tonsil	UBERON:0002372	65.70	gold quality
urinary bladder	UBERON:0001255	65.15	gold quality
right atrium auricular region	UBERON:0006631	64.36	gold quality
spleen	UBERON:0002106	64.27	gold quality
lymph node	UBERON:0000029	63.85	gold quality
ganglionic eminence	UBERON:0004023	63.15	gold quality
gall bladder	UBERON:0002110	62.97	gold quality
superior frontal gyrus	UBERON:0002661	62.13	gold quality
heart	UBERON:0000948	61.62	gold quality
heart left ventricle	UBERON:0002084	61.50	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.25	gold quality
ectocervix	UBERON:0012249	60.86	gold quality
stromal cell of endometrium	CL:0002255	60.33	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	60.12	gold quality
smooth muscle tissue	UBERON:0001135	59.82	gold quality
muscle of leg	UBERON:0001383	59.74	gold quality
lower esophagus	UBERON:0013473	59.67	gold quality
lower esophagus muscularis layer	UBERON:0035833	59.66	gold quality
gastrocnemius	UBERON:0001388	58.98	gold quality
esophagus	UBERON:0001043	58.82	gold quality
lung	UBERON:0002048	58.29	gold quality
colon	UBERON:0001155	57.69	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	57.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.75

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.