HTR5A-AS1

Summary

HTR5A-AS1 (HTR5A antisense RNA 1, HGNC:48956) is a long non-coding RNA gene on chromosome 7q36.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48956
Approved symbol	HTR5A-AS1
Name	HTR5A antisense RNA 1
Location	7q36.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000220575
Ensembl biotype	lncRNA
Entrez	100128264
RNAcentral	URS000075D18F — lncRNA, 2714 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000395731, ENST00000493904, ENST00000655797, ENST00000671665

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000395731 — 2 exons

Exon	Start	End
ENSE00001554074	155067067	155069245
ENSE00003760096	155071034	155071557

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 80.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6629 / max 63.8719, expressed in 79 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
87003	0.2039	55
87002	0.2030	58
86999	0.1508	64
87000	0.0617	35
87001	0.0434	31

Top tissues by expression

47 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
superior frontal gyrus	UBERON:0002661	80.75	gold quality
cerebellum	UBERON:0002037	80.54	gold quality
cerebellar cortex	UBERON:0002129	80.43	gold quality
cerebellar hemisphere	UBERON:0002245	80.35	gold quality
prefrontal cortex	UBERON:0000451	78.93	gold quality
right hemisphere of cerebellum	UBERON:0014890	78.84	gold quality
primary visual cortex	UBERON:0002436	78.00	gold quality
frontal cortex	UBERON:0001870	77.63	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.78	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	76.70	gold quality
right frontal lobe	UBERON:0002810	75.13	gold quality
cerebral cortex	UBERON:0000956	74.25	gold quality
nucleus accumbens	UBERON:0001882	73.84	gold quality
putamen	UBERON:0001874	73.08	gold quality
caudate nucleus	UBERON:0001873	72.54	gold quality
anterior cingulate cortex	UBERON:0009835	72.52	gold quality
brain	UBERON:0000955	72.19	gold quality
multicellular organism	UBERON:0000468	69.75	gold quality
temporal lobe	UBERON:0001871	62.94	gold quality
amygdala	UBERON:0001876	62.62	gold quality
Ammon’s horn	UBERON:0001954	61.18	gold quality
cortical plate	UBERON:0005343	60.54	gold quality
ventricular zone	UBERON:0003053	59.93	gold quality
hypothalamus	UBERON:0001898	58.97	gold quality
corpus callosum	UBERON:0002336	56.84	gold quality
substantia nigra	UBERON:0002038	53.56	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.31	gold quality
placenta	UBERON:0001987	49.64	gold quality
blood	UBERON:0000178	49.49	gold quality
skin of leg	UBERON:0001511	48.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.