HTT-AS

gene

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Also known as HTTAS

Summary

HTT-AS (HTT antisense RNA, HGNC:37118) is a long non-coding RNA gene on chromosome 4p16.3.

Predicted to be involved in regulation of gene expression.

Source: NCBI Gene 100750326 — RefSeq curated summary.

At a glance

Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37118
Approved symbol	HTT-AS
Name	HTT antisense RNA
Location	4p16.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	HTTAS
Ensembl gene	ENSG00000251075
Ensembl biotype	lncRNA
Entrez	100750326
RNAcentral	URS00026A2559 — lncRNA, 5222 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000503893, ENST00000657282, ENST00000660368, ENST00000664062, ENST00000735767, ENST00000735768

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503893 — 4 exons

Exon	Start	End
ENSE00002023647	3069978	3070173
ENSE00002053538	3074426	3074624
ENSE00002065569	3062434	3063700
ENSE00004033603	3049083	3049698

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 75.64.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.64	gold quality
skeletal muscle tissue	UBERON:0001134	59.89	gold quality
cortical plate	UBERON:0005343	59.86	silver quality
lymph node	UBERON:0000029	57.33	gold quality
ventricular zone	UBERON:0003053	57.33	silver quality
ganglionic eminence	UBERON:0004023	56.90	gold quality
prefrontal cortex	UBERON:0000451	54.91	gold quality
superior frontal gyrus	UBERON:0002661	54.43	gold quality
cerebellum	UBERON:0002037	54.10	gold quality
cerebellar cortex	UBERON:0002129	54.05	gold quality
cerebellar hemisphere	UBERON:0002245	53.98	gold quality
right hemisphere of cerebellum	UBERON:0014890	53.68	gold quality
blood	UBERON:0000178	53.50	gold quality
apex of heart	UBERON:0002098	53.38	gold quality
monocyte	CL:0000576	53.25	silver quality
smooth muscle tissue	UBERON:0001135	53.04	gold quality
frontal cortex	UBERON:0001870	52.65	gold quality
liver	UBERON:0002107	52.60	silver quality
granulocyte	CL:0000094	52.22	gold quality
duodenum	UBERON:0002114	52.21	gold quality
anterior cingulate cortex	UBERON:0009835	51.65	gold quality
cerebral cortex	UBERON:0000956	51.43	gold quality
calcaneal tendon	UBERON:0003701	51.25	silver quality
nucleus accumbens	UBERON:0001882	50.54	gold quality
brain	UBERON:0000955	50.39	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.38	gold quality
Brodmann (1909) area 9	UBERON:0013540	50.23	gold quality
right lobe of liver	UBERON:0001114	50.13	silver quality
Ammon’s horn	UBERON:0001954	50.12	gold quality
right frontal lobe	UBERON:0002810	50.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.