ICA1-AS1

Summary

ICA1-AS1 (ICA1 antisense RNA 1, HGNC:55606) is a long non-coding RNA gene on chromosome 7p21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55606
Approved symbol	ICA1-AS1
Name	ICA1 antisense RNA 1
Location	7p21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244239
Ensembl biotype	lncRNA
Entrez	100505938
RNAcentral	URS00007E3C15 — lncRNA, 1073 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000458624, ENST00000716346, ENST00000716347, ENST00000716348, ENST00000716349, ENST00000716350

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458624 — 2 exons

Exon	Start	End
ENSE00001728111	8262233	8262419
ENSE00001779133	8262580	8262821

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 95.15.

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.15	gold quality
body of pancreas	UBERON:0001150	84.32	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	84.09	gold quality
right atrium auricular region	UBERON:0006631	83.68	gold quality
pituitary gland	UBERON:0000007	83.24	gold quality
adenohypophysis	UBERON:0002196	81.29	gold quality
mucosa of transverse colon	UBERON:0004991	80.59	gold quality
pancreas	UBERON:0001264	80.50	gold quality
heart left ventricle	UBERON:0002084	79.97	gold quality
saliva-secreting gland	UBERON:0001044	79.26	gold quality
minor salivary gland	UBERON:0001830	79.10	gold quality
apex of heart	UBERON:0002098	78.54	gold quality
heart	UBERON:0000948	78.53	gold quality
putamen	UBERON:0001874	76.09	gold quality
caudate nucleus	UBERON:0001873	74.39	gold quality
prostate gland	UBERON:0002367	74.36	gold quality
islet of Langerhans	UBERON:0000006	74.02	gold quality
nucleus accumbens	UBERON:0001882	73.77	gold quality
adult mammalian kidney	UBERON:0000082	73.68	gold quality
ganglionic eminence	UBERON:0004023	73.63	gold quality
prefrontal cortex	UBERON:0000451	73.59	gold quality
superior frontal gyrus	UBERON:0002661	73.57	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.39	gold quality
bone marrow cell	CL:0002092	73.10	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	72.88	gold quality
anterior cingulate cortex	UBERON:0009835	72.63	gold quality
primary visual cortex	UBERON:0002436	72.60	gold quality
frontal cortex	UBERON:0001870	72.54	gold quality
left lobe of thyroid gland	UBERON:0001120	72.31	gold quality
colonic epithelium	UBERON:0000397	72.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.