ICAM4-AS1

Summary

ICAM4-AS1 (ICAM4 antisense RNA 1, HGNC:55990) is a long non-coding RNA gene on chromosome 19p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55990
Approved symbol	ICAM4-AS1
Name	ICAM4 antisense RNA 1
Location	19p13.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	LncRNA-ECM, ICR, AC011511.5
Ensembl gene	ENSG00000267607
Ensembl biotype	lncRNA
Entrez	123706506
RNAcentral	URS000049689E — lncRNA, 3219 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000589379, ENST00000724881

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000589379 — 1 exons

Exon	Start	End
ENSE00002935784	10285801	10289019

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 63.27.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stromal cell of endometrium	CL:0002255	63.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.66	gold quality
bone marrow cell	CL:0002092	62.21	silver quality
upper lobe of left lung	UBERON:0008952	60.80	gold quality
lung	UBERON:0002048	60.29	gold quality
liver	UBERON:0002107	60.10	gold quality
skeletal muscle tissue	UBERON:0001134	59.97	silver quality
left uterine tube	UBERON:0001303	58.99	gold quality
right lobe of liver	UBERON:0001114	57.97	gold quality
granulocyte	CL:0000094	57.30	gold quality
muscle tissue	UBERON:0002385	56.16	gold quality
bone marrow	UBERON:0002371	55.79	gold quality
omental fat pad	UBERON:0010414	55.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.70	gold quality
cortex of kidney	UBERON:0001225	54.18	gold quality
leukocyte	CL:0000738	53.78	silver quality
blood	UBERON:0000178	53.71	gold quality
monocyte	CL:0000576	53.14	silver quality
right lung	UBERON:0002167	52.71	gold quality
fallopian tube	UBERON:0003889	52.46	gold quality
adipose tissue	UBERON:0001013	51.34	gold quality
lymph node	UBERON:0000029	51.21	gold quality
endometrium	UBERON:0001295	51.20	gold quality
descending thoracic aorta	UBERON:0002345	51.14	gold quality
islet of Langerhans	UBERON:0000006	50.93	gold quality
kidney	UBERON:0002113	50.77	gold quality
urinary bladder	UBERON:0001255	50.61	gold quality
muscle of leg	UBERON:0001383	50.60	gold quality
pancreas	UBERON:0001264	50.39	gold quality
myometrium	UBERON:0001296	50.23	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	18.45
E-MTAB-9543	yes	13.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.