ICE1-DT

Summary

ICE1-DT (ICE1 divergent transcript, HGNC:58997) is a long non-coding RNA gene on chromosome 5p15.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58997
Approved symbol	ICE1-DT
Name	ICE1 divergent transcript
Location	5p15.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286753
Ensembl biotype	lncRNA
Entrez	101929200

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000669435, ENST00000686499, ENST00000690642, ENST00000693678, ENST00000725525, ENST00000725526, ENST00000725527, ENST00000725528, ENST00000725529, ENST00000725530, ENST00000725531, ENST00000725532, ENST00000725533, ENST00000725534

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000669435 — 3 exons

Exon	Start	End
ENSE00003887504	5420751	5420840
ENSE00004049159	5421403	5422340
ENSE00004049170	5389853	5391203

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 83.20.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.20	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.41	gold quality
colonic epithelium	UBERON:0000397	70.14	silver quality
ventricular zone	UBERON:0003053	63.65	gold quality
cortical plate	UBERON:0005343	63.12	gold quality
ganglionic eminence	UBERON:0004023	62.77	gold quality
granulocyte	CL:0000094	62.66	gold quality
islet of Langerhans	UBERON:0000006	61.09	gold quality
skeletal muscle tissue	UBERON:0001134	59.49	gold quality
tonsil	UBERON:0002372	59.01	gold quality
stromal cell of endometrium	CL:0002255	58.19	gold quality
prefrontal cortex	UBERON:0000451	58.18	gold quality
lymph node	UBERON:0000029	57.81	gold quality
right lobe of liver	UBERON:0001114	56.90	gold quality
liver	UBERON:0002107	56.72	gold quality
corpus callosum	UBERON:0002336	56.30	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.22	gold quality
pancreas	UBERON:0001264	56.10	gold quality
lower esophagus mucosa	UBERON:0035834	55.96	gold quality
right coronary artery	UBERON:0001625	55.88	gold quality
superior frontal gyrus	UBERON:0002661	55.54	gold quality
frontal cortex	UBERON:0001870	55.39	gold quality
heart left ventricle	UBERON:0002084	55.34	gold quality
leukocyte	CL:0000738	55.27	gold quality
popliteal artery	UBERON:0002250	55.18	gold quality
tibial artery	UBERON:0007610	55.15	gold quality
urinary bladder	UBERON:0001255	55.10	gold quality
duodenum	UBERON:0002114	54.98	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.94	gold quality
thoracic aorta	UBERON:0001515	54.86	gold quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.