IDH2-DT

Summary

IDH2-DT (IDH2 divergent transcript, HGNC:53154) is a long non-coding RNA gene on chromosome 15q26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53154
Approved symbol	IDH2-DT
Name	IDH2 divergent transcript
Location	15q26.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259685
Ensembl biotype	lncRNA
Entrez	105370966
RNAcentral	URS0000BC45DA — lncRNA, 496 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000561101, ENST00000824295, ENST00000824296, ENST00000824297, ENST00000824298, ENST00000824299, ENST00000824300, ENST00000824301, ENST00000824302, ENST00000824303, ENST00000824304, ENST00000824305

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561101 — 5 exons

Exon	Start	End
ENSE00002537267	90102649	90102763
ENSE00002550055	90117980	90118097
ENSE00002557190	90133397	90133632
ENSE00002564705	90103380	90103452
ENSE00003854325	90137907	90138016

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 72.50.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
substantia nigra	UBERON:0002038	72.50	gold quality
putamen	UBERON:0001874	70.01	gold quality
caudate nucleus	UBERON:0001873	70.00	gold quality
amygdala	UBERON:0001876	69.67	gold quality
temporal lobe	UBERON:0001871	69.57	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	69.10	gold quality
skeletal muscle tissue	UBERON:0001134	68.49	gold quality
nucleus accumbens	UBERON:0001882	68.42	gold quality
muscle tissue	UBERON:0002385	66.53	gold quality
tonsil	UBERON:0002372	66.30	silver quality
hypothalamus	UBERON:0001898	66.02	gold quality
Ammon’s horn	UBERON:0001954	65.22	gold quality
anterior cingulate cortex	UBERON:0009835	63.70	gold quality
brain	UBERON:0000955	63.67	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.63	gold quality
heart left ventricle	UBERON:0002084	62.68	gold quality
cerebral cortex	UBERON:0000956	62.60	gold quality
prefrontal cortex	UBERON:0000451	62.32	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.31	gold quality
Brodmann (1909) area 9	UBERON:0013540	62.07	gold quality
apex of heart	UBERON:0002098	61.51	gold quality
frontal cortex	UBERON:0001870	61.48	gold quality
right frontal lobe	UBERON:0002810	61.19	gold quality
primary visual cortex	UBERON:0002436	60.39	gold quality
adult mammalian kidney	UBERON:0000082	59.96	gold quality
kidney	UBERON:0002113	59.87	gold quality
muscle of leg	UBERON:0001383	59.10	gold quality
gastrocnemius	UBERON:0001388	57.93	gold quality
liver	UBERON:0002107	57.25	gold quality
heart	UBERON:0000948	56.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.