IFITM3-AS1

Summary

IFITM3-AS1 (IFITM3 antisense RNA 1, HGNC:58185) is a long non-coding RNA gene on chromosome 11p15.5.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58185
Approved symbol	IFITM3-AS1
Name	IFITM3 antisense RNA 1
Location	11p15.5
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000251661
Ensembl biotype	lncRNA
Entrez	105376505
RNAcentral	URS0002A634CB — lncRNA, 1194 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 22 — 22 lncRNA

ENST00000508004, ENST00000524824, ENST00000531076, ENST00000534483, ENST00000602429, ENST00000602756, ENST00000688089, ENST00000717735, ENST00000717736, ENST00000717737, ENST00000717738, ENST00000755701, ENST00000755702, ENST00000755703, ENST00000755704, ENST00000755705, ENST00000755706, ENST00000755707, ENST00000755708, ENST00000755709, ENST00000755710, ENST00000755711

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508004 — 2 exons

Exon	Start	End
ENSE00002155025	318640	318746
ENSE00002166905	319357	319615

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 86.61.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	86.61	gold quality
left uterine tube	UBERON:0001303	84.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.89	gold quality
blood	UBERON:0000178	83.60	gold quality
mucosa of stomach	UBERON:0001199	83.06	gold quality
granulocyte	CL:0000094	81.65	gold quality
calcaneal tendon	UBERON:0003701	79.15	gold quality
descending thoracic aorta	UBERON:0002345	77.94	gold quality
right coronary artery	UBERON:0001625	77.85	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.61	gold quality
body of uterus	UBERON:0009853	77.40	gold quality
fallopian tube	UBERON:0003889	76.96	gold quality
right ovary	UBERON:0002118	76.55	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	76.27	gold quality
lower esophagus	UBERON:0013473	76.25	gold quality
lower esophagus muscularis layer	UBERON:0035833	76.25	gold quality
spleen	UBERON:0002106	76.12	gold quality
left ovary	UBERON:0002119	75.92	gold quality
ovary	UBERON:0000992	75.76	gold quality
muscle layer of sigmoid colon	UBERON:0035805	75.63	gold quality
thoracic aorta	UBERON:0001515	75.30	gold quality
myometrium	UBERON:0001296	75.25	gold quality
left coronary artery	UBERON:0001626	75.17	gold quality
ascending aorta	UBERON:0001496	75.08	gold quality
tibial nerve	UBERON:0001323	74.62	gold quality
tibial artery	UBERON:0007610	74.47	gold quality
popliteal artery	UBERON:0002250	74.46	gold quality
endocervix	UBERON:0000458	74.37	gold quality
omental fat pad	UBERON:0010414	74.11	gold quality
ectocervix	UBERON:0012249	73.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.