IGF1R-AS2

Summary

IGF1R-AS2 (IGF1R antisense RNA 2, HGNC:58474) is a long non-coding RNA gene on chromosome 15q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58474
Approved symbol	IGF1R-AS2
Name	IGF1R antisense RNA 2
Location	15q26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259621
Ensembl biotype	lncRNA
Entrez	141974269

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000558736

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558736 — 2 exons

Exon	Start	End
ENSE00002544061	98880659	98880852
ENSE00002566366	98893467	98893535

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 91.18.

Top tissues by expression

97 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.18	gold quality
corpus callosum	UBERON:0002336	76.23	gold quality
adrenal tissue	UBERON:0018303	75.54	gold quality
skeletal muscle tissue	UBERON:0001134	70.97	gold quality
cortex of kidney	UBERON:0001225	66.37	gold quality
smooth muscle tissue	UBERON:0001135	65.89	gold quality
blood	UBERON:0000178	65.17	gold quality
monocyte	CL:0000576	65.10	gold quality
superior frontal gyrus	UBERON:0002661	64.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	64.38	gold quality
kidney	UBERON:0002113	62.33	gold quality
vermiform appendix	UBERON:0001154	62.07	gold quality
calcaneal tendon	UBERON:0003701	61.19	gold quality
islet of Langerhans	UBERON:0000006	60.95	gold quality
prefrontal cortex	UBERON:0000451	60.64	gold quality
tonsil	UBERON:0002372	60.64	silver quality
muscle of leg	UBERON:0001383	60.30	gold quality
liver	UBERON:0002107	59.14	gold quality
gastrocnemius	UBERON:0001388	58.83	gold quality
lung	UBERON:0002048	58.59	gold quality
stomach	UBERON:0000945	58.25	gold quality
adrenal gland	UBERON:0002369	57.86	gold quality
tibial artery	UBERON:0007610	57.79	gold quality
adult mammalian kidney	UBERON:0000082	57.59	gold quality
heart	UBERON:0000948	57.11	gold quality
left adrenal gland cortex	UBERON:0035825	55.43	gold quality
ectocervix	UBERON:0012249	55.03	gold quality
subcutaneous adipose tissue	UBERON:0002190	54.92	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.87	gold quality
heart left ventricle	UBERON:0002084	54.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.