IGF2BP2-AS1

Summary

IGF2BP2-AS1 (IGF2BP2 antisense RNA 1, HGNC:32674) is a long non-coding RNA gene on chromosome 3q27.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32674
Approved symbol	IGF2BP2-AS1
Name	IGF2BP2 antisense RNA 1
Location	3q27.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ32900
Ensembl gene	ENSG00000163915
Ensembl biotype	lncRNA
Entrez	646600
RNAcentral	URS00007C5419 — lncRNA, 1924 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000296270, ENST00000456447, ENST00000465364, ENST00000470754, ENST00000496717

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000296270 — 2 exons

Exon	Start	End
ENSE00001079600	185713292	185713488
ENSE00001235731	185716441	185718167

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 86.04.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1712 / max 93.2396, expressed in 50 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
40252	0.1712	50

Top tissues by expression

222 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	86.04	gold quality
adrenal tissue	UBERON:0018303	82.19	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.95	gold quality
colonic epithelium	UBERON:0000397	76.53	gold quality
buccal mucosa cell	CL:0002336	75.93	gold quality
bone marrow cell	CL:0002092	70.88	silver quality
ventricular zone	UBERON:0003053	60.61	gold quality
calcaneal tendon	UBERON:0003701	60.07	gold quality
monocyte	CL:0000576	57.74	gold quality
stromal cell of endometrium	CL:0002255	57.26	gold quality
mucosa of transverse colon	UBERON:0004991	56.98	gold quality
tendon	UBERON:0000043	55.68	gold quality
adrenal gland	UBERON:0002369	54.45	gold quality
mucosa of stomach	UBERON:0001199	54.36	gold quality
hindlimb stylopod muscle	UBERON:0004252	54.11	silver quality
tonsil	UBERON:0002372	53.99	gold quality
stomach	UBERON:0000945	53.54	gold quality
lower lobe of lung	UBERON:0008949	53.29	silver quality
tendon of biceps brachii	UBERON:0008188	53.25	gold quality
upper leg skin	UBERON:0004262	51.61	silver quality
left testis	UBERON:0004533	51.53	gold quality
bone marrow	UBERON:0002371	51.37	gold quality
kidney	UBERON:0002113	51.33	gold quality
testis	UBERON:0000473	51.29	gold quality
lung	UBERON:0002048	51.08	gold quality
islet of Langerhans	UBERON:0000006	50.76	gold quality
adult mammalian kidney	UBERON:0000082	50.57	gold quality
right testis	UBERON:0004534	49.84	gold quality
muscle of leg	UBERON:0001383	49.72	gold quality
pancreas	UBERON:0001264	49.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.78

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Knockdown of lncRNA IGF2BP2-AS1 inhibits proliferation and migration of oral squamous cell carcinoma cells via the Wnt/beta-catenin pathway. (PMID:34637162)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.