IGSF11-AS1

Summary

IGSF11-AS1 (IGSF11 antisense RNA 1, HGNC:40777) is a long non-coding RNA gene on chromosome 3q13.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40777
Approved symbol	IGSF11-AS1
Name	IGSF11 antisense RNA 1
Location	3q13.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239877
Ensembl biotype	lncRNA
Entrez	100506765
RNAcentral	URS000075E47D — lncRNA, 1601 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000477009, ENST00000669213

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000477009 — 4 exons

Exon	Start	End
ENSE00001821264	118944862	118944990
ENSE00001862487	118945868	118946035
ENSE00004263196	118947049	118948241
ENSE00004263197	118943072	118943186

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 99.62.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0569 / max 48.2661, expressed in 5 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
38065	0.0301	3
38067	0.0221	3
38066	0.0047	4

Top tissues by expression

180 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	99.62	gold quality
left testis	UBERON:0004533	88.05	gold quality
right testis	UBERON:0004534	86.52	gold quality
testis	UBERON:0000473	85.44	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.24	gold quality
adult organism	UBERON:0007023	69.55	gold quality
ganglionic eminence	UBERON:0004023	63.34	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.28	gold quality
corpus callosum	UBERON:0002336	56.88	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
epithelial cell of pancreas	CL:0000083	53.56	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
skin of leg	UBERON:0001511	52.48	gold quality
sural nerve	UBERON:0015488	52.43	silver quality
monocyte	CL:0000576	51.62	silver quality
upper lobe of lung	UBERON:0008948	51.29	silver quality
lower lobe of lung	UBERON:0008949	51.19	silver quality
cauda epididymis	UBERON:0004360	51.01	gold quality
pancreatic ductal cell	CL:0002079	51.00	silver quality
myocardium	UBERON:0002349	50.25	gold quality
muscle of leg	UBERON:0001383	47.62	gold quality
gastrocnemius	UBERON:0001388	47.10	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
deltoid	UBERON:0001476	46.87	gold quality
prefrontal cortex	UBERON:0000451	46.86	silver quality
anatomical system	UBERON:0000467	46.43	gold quality
material anatomical entity	UBERON:0000465	46.17	gold quality
quadriceps femoris	UBERON:0001377	46.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.