IGSF21-AS1

Summary

IGSF21-AS1 (IGSF21 antisense RNA 1, HGNC:41190) is a long non-coding RNA gene on chromosome 1p36.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41190
Approved symbol	IGSF21-AS1
Name	IGSF21 antisense RNA 1
Location	1p36.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230035
Ensembl biotype	lncRNA
Entrez	105376814
RNAcentral	URS0002A54664 — lncRNA, 539 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000419667, ENST00000718980, ENST00000718981, ENST00000718982

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419667 — 4 exons

Exon	Start	End
ENSE00001641263	18166929	18167024
ENSE00001679066	18167747	18167763
ENSE00001748662	18179052	18179346
ENSE00001776577	18176153	18176174

Expression profiles

Bgee: expression breadth broad, 66 present calls, max score 69.22.

Top tissues by expression

66 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	69.22	gold quality
testis	UBERON:0000473	68.02	gold quality
right testis	UBERON:0004534	66.96	gold quality
blood	UBERON:0000178	61.26	gold quality
islet of Langerhans	UBERON:0000006	60.74	gold quality
lymph node	UBERON:0000029	57.45	gold quality
monocyte	CL:0000576	55.83	gold quality
calcaneal tendon	UBERON:0003701	55.15	gold quality
vermiform appendix	UBERON:0001154	55.02	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.25	gold quality
superior frontal gyrus	UBERON:0002661	54.05	gold quality
multicellular organism	UBERON:0000468	53.81	gold quality
prefrontal cortex	UBERON:0000451	52.10	gold quality
cerebellum	UBERON:0002037	49.11	gold quality
cerebellar cortex	UBERON:0002129	48.98	gold quality
cerebellar hemisphere	UBERON:0002245	48.71	gold quality
right hemisphere of cerebellum	UBERON:0014890	47.91	gold quality
skin of abdomen	UBERON:0001416	47.40	gold quality
body of stomach	UBERON:0001161	47.34	gold quality
zone of skin	UBERON:0000014	46.99	gold quality
gastrocnemius	UBERON:0001388	46.55	gold quality
tonsil	UBERON:0002372	46.53	gold quality
right frontal lobe	UBERON:0002810	46.52	gold quality
brain	UBERON:0000955	46.22	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	45.92	gold quality
right atrium auricular region	UBERON:0006631	45.63	gold quality
Brodmann (1909) area 9	UBERON:0013540	43.92	gold quality
heart left ventricle	UBERON:0002084	43.90	silver quality
esophagus mucosa	UBERON:0002469	43.81	silver quality
tibial artery	UBERON:0007610	43.48	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.