IGSF22-AS1

Summary

IGSF22-AS1 (IGSF22 antisense RNA 1, HGNC:55511) is a long non-coding RNA gene on chromosome 11p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55511
Approved symbol	IGSF22-AS1
Name	IGSF22 antisense RNA 1
Location	11p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254966
Ensembl biotype	lncRNA
Entrez	120883618
RNAcentral	URS00026A1F9D — lncRNA, 2249 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000527285, ENST00000776877, ENST00000776878

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527285 — 3 exons

Exon	Start	End
ENSE00002171937	18707278	18707393
ENSE00002180096	18740424	18740568
ENSE00002185009	18706537	18707149

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 85.89.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.89	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.90	silver quality
skin of leg	UBERON:0001511	77.74	gold quality
zone of skin	UBERON:0000014	76.28	gold quality
skin of abdomen	UBERON:0001416	74.41	gold quality
left ovary	UBERON:0002119	73.56	gold quality
ovary	UBERON:0000992	72.35	gold quality
right frontal lobe	UBERON:0002810	72.07	gold quality
right ovary	UBERON:0002118	71.94	gold quality
popliteal artery	UBERON:0002250	71.26	gold quality
tibial artery	UBERON:0007610	71.26	gold quality
right lung	UBERON:0002167	70.70	gold quality
anterior cingulate cortex	UBERON:0009835	70.55	gold quality
endocervix	UBERON:0000458	70.42	gold quality
body of uterus	UBERON:0009853	70.27	gold quality
frontal cortex	UBERON:0001870	70.17	gold quality
right coronary artery	UBERON:0001625	69.85	gold quality
ventricular zone	UBERON:0003053	69.81	gold quality
descending thoracic aorta	UBERON:0002345	69.70	gold quality
subcutaneous adipose tissue	UBERON:0002190	69.57	gold quality
thoracic aorta	UBERON:0001515	69.42	gold quality
ascending aorta	UBERON:0001496	69.40	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.37	gold quality
superior frontal gyrus	UBERON:0002661	69.24	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.22	gold quality
prefrontal cortex	UBERON:0000451	69.16	gold quality
cerebral cortex	UBERON:0000956	69.16	gold quality
pituitary gland	UBERON:0000007	69.00	gold quality
cortical plate	UBERON:0005343	68.88	gold quality
putamen	UBERON:0001874	68.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.45

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.