IKBKB-DT

Summary

IKBKB-DT (IKBKB divergent transcript, HGNC:55254) is a long non-coding RNA gene on chromosome 8p11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55254
Approved symbol	IKBKB-DT
Name	IKBKB divergent transcript
Location	8p11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-231D20.2, ALAL-1, IKBKBAS
Ensembl gene	ENSG00000253408
Ensembl biotype	lncRNA
Entrez	101929897
RNAcentral	URS0002A1461B — lncRNA, 939 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 25 lncRNA

ENST00000518213, ENST00000518994, ENST00000520890, ENST00000521470, ENST00000521802, ENST00000523459, ENST00000661382, ENST00000717950, ENST00000717951, ENST00000717952, ENST00000717953, ENST00000717954, ENST00000717955, ENST00000717956, ENST00000717957, ENST00000810758, ENST00000810759, ENST00000810760, ENST00000810761, ENST00000810762, ENST00000810763, ENST00000810764, ENST00000810765, ENST00000810766, ENST00000810767

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000518213 — 4 exons

Exon	Start	End
ENSE00002119589	42270651	42271253
ENSE00002122603	42263329	42263472
ENSE00003877648	42265615	42266396
ENSE00003879603	42233674	42233859

Expression profiles

Bgee: expression breadth ubiquitous, 145 present calls, max score 93.08.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	93.08	gold quality
right testis	UBERON:0004534	92.50	gold quality
testis	UBERON:0000473	89.63	gold quality
sperm	CL:0000019	88.18	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.09	gold quality
cardiac muscle of right atrium	UBERON:0003379	83.85	gold quality
left ventricle myocardium	UBERON:0006566	83.35	gold quality
kidney epithelium	UBERON:0004819	82.96	gold quality
upper arm skin	UBERON:0004263	82.35	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.54	silver quality
tibialis anterior	UBERON:0001385	78.70	silver quality
nasal cavity epithelium	UBERON:0005384	77.75	gold quality
superficial temporal artery	UBERON:0001614	76.69	gold quality
myocardium	UBERON:0002349	76.30	gold quality
mucosa of paranasal sinus	UBERON:0005030	72.93	gold quality
epithelial cell of pancreas	CL:0000083	71.96	gold quality
quadriceps femoris	UBERON:0001377	71.83	gold quality
colonic epithelium	UBERON:0000397	71.75	silver quality
vastus lateralis	UBERON:0001379	71.05	gold quality
deltoid	UBERON:0001476	70.69	gold quality
endothelial cell	CL:0000115	70.65	gold quality
ileal mucosa	UBERON:0000331	69.62	silver quality
adult organism	UBERON:0007023	69.59	gold quality
bone marrow cell	CL:0002092	69.21	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	69.10	gold quality
epithelium of nasopharynx	UBERON:0001951	68.47	gold quality
layer of synovial tissue	UBERON:0007616	68.31	gold quality
lateral globus pallidus	UBERON:0002476	68.15	gold quality
subthalamic nucleus	UBERON:0001906	67.40	gold quality
skeletal muscle tissue	UBERON:0001134	67.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.84

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.