IL12B-AS1

Summary

IL12B-AS1 (IL12B antisense RNA 1, HGNC:58156) is a long non-coding RNA gene on chromosome 5q33.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58156
Approved symbol	IL12B-AS1
Name	IL12B antisense RNA 1
Location	5q33.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	Uc003xsl.1
Ensembl gene	ENSG00000249738
Ensembl biotype	lncRNA
Entrez	285626
RNAcentral	URS000008862D — lncRNA, 1580 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 53 — 53 lncRNA

ENST00000515337, ENST00000521472, ENST00000635333, ENST00000636261, ENST00000636819, ENST00000636943, ENST00000641150, ENST00000641685, ENST00000641961, ENST00000642094, ENST00000648969, ENST00000764988, ENST00000764989, ENST00000764990, ENST00000764991, ENST00000764992, ENST00000764993, ENST00000764994, ENST00000764995, ENST00000764996, ENST00000764997, ENST00000764998, ENST00000764999, ENST00000765000, ENST00000765001, ENST00000765002, ENST00000765003, ENST00000765004, ENST00000765005, ENST00000765006, ENST00000765007, ENST00000765008, ENST00000765009, ENST00000765010, ENST00000765011, ENST00000765012, ENST00000765013, ENST00000765014, ENST00000765015, ENST00000765016, ENST00000765017, ENST00000765018, ENST00000765019, ENST00000765020, ENST00000765021, ENST00000765022, ENST00000811686, ENST00000811687, ENST00000811688, ENST00000811689, ENST00000811690, ENST00000811691, ENST00000811692

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000515337 — 5 exons

Exon	Start	End
ENSE00002058927	159362208	159362834
ENSE00002061392	159332782	159333003
ENSE00002068563	159347516	159347605
ENSE00002086704	159331518	159332040
ENSE00002531093	159354004	159354121

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 87.12.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.12	gold quality
corpus callosum	UBERON:0002336	74.28	gold quality
right testis	UBERON:0004534	73.85	gold quality
left testis	UBERON:0004533	73.33	gold quality
testis	UBERON:0000473	72.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.45	gold quality
bone marrow cell	CL:0002092	69.10	silver quality
tonsil	UBERON:0002372	67.78	gold quality
pituitary gland	UBERON:0000007	64.90	gold quality
adenohypophysis	UBERON:0002196	62.41	gold quality
ganglionic eminence	UBERON:0004023	59.31	gold quality
prefrontal cortex	UBERON:0000451	59.01	gold quality
lymph node	UBERON:0000029	58.96	gold quality
ventricular zone	UBERON:0003053	58.84	silver quality
superior frontal gyrus	UBERON:0002661	57.20	gold quality
bone marrow	UBERON:0002371	57.16	silver quality
vermiform appendix	UBERON:0001154	56.64	gold quality
adult mammalian kidney	UBERON:0000082	56.39	gold quality
frontal cortex	UBERON:0001870	56.02	gold quality
cortex of kidney	UBERON:0001225	55.57	gold quality
kidney	UBERON:0002113	55.52	gold quality
monocyte	CL:0000576	55.50	gold quality
duodenum	UBERON:0002114	54.89	gold quality
right lobe of liver	UBERON:0001114	54.73	gold quality
brain	UBERON:0000955	54.59	gold quality
substantia nigra	UBERON:0002038	54.50	gold quality
liver	UBERON:0002107	54.42	gold quality
putamen	UBERON:0001874	54.41	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	54.29	gold quality
blood	UBERON:0000178	54.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.56

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.