IL1R1-AS1

Summary

IL1R1-AS1 (IL1R1 antisense RNA 1, HGNC:53898) is a long non-coding RNA gene on chromosome 2q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53898
Approved symbol	IL1R1-AS1
Name	IL1R1 antisense RNA 1
Location	2q12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC007271.3
Ensembl gene	ENSG00000226925
Ensembl biotype	lncRNA
Entrez	112577460
RNAcentral	URS0000056BD1 — lncRNA, 382 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000428188, ENST00000799942, ENST00000799943, ENST00000799944, ENST00000799945, ENST00000799946

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428188 — 3 exons

Exon	Start	End
ENSE00001612991	102179912	102180001
ENSE00004188963	102172621	102172697
ENSE00004188964	102181894	102182155

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 92.53.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.90	gold quality
endometrium	UBERON:0001295	66.03	gold quality
gall bladder	UBERON:0002110	65.09	gold quality
stromal cell of endometrium	CL:0002255	64.80	gold quality
vermiform appendix	UBERON:0001154	64.50	gold quality
omental fat pad	UBERON:0010414	62.28	gold quality
adipose tissue	UBERON:0001013	62.22	gold quality
subcutaneous adipose tissue	UBERON:0002190	62.19	gold quality
liver	UBERON:0002107	60.97	gold quality
blood	UBERON:0000178	59.84	gold quality
right lobe of liver	UBERON:0001114	59.84	gold quality
superior frontal gyrus	UBERON:0002661	59.75	gold quality
bone marrow	UBERON:0002371	59.52	gold quality
endocervix	UBERON:0000458	59.30	gold quality
upper lobe of left lung	UBERON:0008952	58.98	gold quality
monocyte	CL:0000576	58.96	gold quality
prefrontal cortex	UBERON:0000451	58.88	gold quality
calcaneal tendon	UBERON:0003701	58.81	gold quality
islet of Langerhans	UBERON:0000006	58.45	gold quality
lung	UBERON:0002048	57.94	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.88	gold quality
right atrium auricular region	UBERON:0006631	56.78	gold quality
muscle of leg	UBERON:0001383	56.38	gold quality
left uterine tube	UBERON:0001303	56.16	gold quality
prostate gland	UBERON:0002367	56.12	gold quality
left adrenal gland cortex	UBERON:0035825	55.94	gold quality
right ovary	UBERON:0002118	55.91	gold quality
thoracic mammary gland	UBERON:0005200	55.89	gold quality
gastrocnemius	UBERON:0001388	55.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	8.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.