IL21R-AS1

Summary

IL21R-AS1 (IL21R antisense RNA 1, HGNC:27551) is a long non-coding RNA gene on chromosome 16p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27551
Approved symbol	IL21R-AS1
Name	IL21R antisense RNA 1
Location	16p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259954
Ensembl biotype	lncRNA
Entrez	283888
RNAcentral	URS000075B66C — lncRNA, 2632 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000563191

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563191 — 3 exons

Exon	Start	End
ENSE00002577391	27447669	27449806
ENSE00002591700	27453097	27453393
ENSE00002596311	27452743	27452922

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 68.28.

Top tissues by expression

219 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	68.28	silver quality
pituitary gland	UBERON:0000007	67.08	gold quality
cerebellar hemisphere	UBERON:0002245	66.99	gold quality
cerebellar cortex	UBERON:0002129	66.84	gold quality
right hemisphere of cerebellum	UBERON:0014890	66.60	gold quality
sperm	CL:0000019	66.43	gold quality
cerebellum	UBERON:0002037	65.99	gold quality
nucleus accumbens	UBERON:0001882	65.32	gold quality
lower esophagus mucosa	UBERON:0035834	64.99	gold quality
adenohypophysis	UBERON:0002196	64.64	gold quality
endothelial cell	CL:0000115	63.64	gold quality
pigmented layer of retina	UBERON:0001782	62.61	silver quality
cortical plate	UBERON:0005343	62.28	gold quality
putamen	UBERON:0001874	62.14	gold quality
hypothalamus	UBERON:0001898	61.71	gold quality
caudate nucleus	UBERON:0001873	61.21	gold quality
ganglionic eminence	UBERON:0004023	61.01	gold quality
right frontal lobe	UBERON:0002810	60.57	gold quality
amygdala	UBERON:0001876	59.37	gold quality
vermiform appendix	UBERON:0001154	59.19	gold quality
brain	UBERON:0000955	59.07	gold quality
granulocyte	CL:0000094	58.64	gold quality
lymph node	UBERON:0000029	58.53	gold quality
Brodmann (1909) area 9	UBERON:0013540	58.53	gold quality
anterior cingulate cortex	UBERON:0009835	58.45	gold quality
forebrain	UBERON:0001890	58.28	gold quality
substantia nigra pars reticulata	UBERON:0001966	58.25	gold quality
primary visual cortex	UBERON:0002436	58.16	gold quality
caecum	UBERON:0001153	57.79	gold quality
oocyte	CL:0000023	57.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.