IL2RB-AS1

Summary

IL2RB-AS1 (IL2RB and C1QTNF6 antisense RNA 1, HGNC:40300) is a long non-coding RNA gene on chromosome 22q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40300
Approved symbol	IL2RB-AS1
Name	IL2RB and C1QTNF6 antisense RNA 1
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235237
Ensembl biotype	lncRNA
Entrez	139281655
RNAcentral	URS0002A2A3B1 — lncRNA, 725 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000419128

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419128 — 2 exons

Exon	Start	End
ENSE00004275243	37182429	37182931
ENSE00004275244	37166743	37166964

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 62.87.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	62.87	silver quality
right lobe of liver	UBERON:0001114	62.56	gold quality
lymph node	UBERON:0000029	62.22	gold quality
granulocyte	CL:0000094	61.67	gold quality
liver	UBERON:0002107	60.92	gold quality
prefrontal cortex	UBERON:0000451	60.09	gold quality
ventricular zone	UBERON:0003053	59.77	gold quality
endometrium	UBERON:0001295	59.45	gold quality
right adrenal gland cortex	UBERON:0035827	59.34	gold quality
vermiform appendix	UBERON:0001154	59.11	gold quality
right uterine tube	UBERON:0001302	59.10	gold quality
blood	UBERON:0000178	59.05	gold quality
right adrenal gland	UBERON:0001233	58.86	gold quality
ganglionic eminence	UBERON:0004023	58.69	gold quality
smooth muscle tissue	UBERON:0001135	58.64	gold quality
tonsil	UBERON:0002372	57.87	gold quality
left adrenal gland cortex	UBERON:0035825	57.77	gold quality
placenta	UBERON:0001987	57.58	gold quality
cortical plate	UBERON:0005343	57.42	silver quality
gall bladder	UBERON:0002110	57.40	gold quality
adrenal gland	UBERON:0002369	57.29	gold quality
stromal cell of endometrium	CL:0002255	56.98	gold quality
left adrenal gland	UBERON:0001234	56.94	gold quality
left uterine tube	UBERON:0001303	56.50	gold quality
right coronary artery	UBERON:0001625	56.11	gold quality
superior frontal gyrus	UBERON:0002661	55.51	gold quality
spleen	UBERON:0002106	55.27	gold quality
myometrium	UBERON:0001296	55.24	gold quality
frontal cortex	UBERON:0001870	55.15	gold quality
calcaneal tendon	UBERON:0003701	53.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.