IL6ST-DT

Summary

IL6ST-DT (IL6ST divergent transcript, HGNC:55804) is a long non-coding RNA gene on chromosome 5q11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55804
Approved symbol	IL6ST-DT
Name	IL6ST divergent transcript
Location	5q11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227908
Ensembl biotype	lncRNA
Entrez	441072
RNAcentral	URS000075C2D9 — lncRNA, 2300 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000500093, ENST00000686866, ENST00000720008, ENST00000720009, ENST00000720010, ENST00000720011, ENST00000720012

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500093 — 2 exons

Exon	Start	End
ENSE00004038278	55995151	55995554
ENSE00004038284	56001749	56003649

Expression profiles

Bgee: expression breadth ubiquitous, 143 present calls, max score 79.53.

Top tissues by expression

233 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	79.53	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.60	gold quality
ganglionic eminence	UBERON:0004023	60.63	gold quality
ventricular zone	UBERON:0003053	60.34	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.00	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.21	gold quality
stromal cell of endometrium	CL:0002255	54.45	gold quality
calcaneal tendon	UBERON:0003701	54.20	gold quality
right uterine tube	UBERON:0001302	53.98	gold quality
monocyte	CL:0000576	53.88	gold quality
cerebellar cortex	UBERON:0002129	53.24	gold quality
cerebellar hemisphere	UBERON:0002245	53.17	gold quality
rectum	UBERON:0001052	52.95	gold quality
prefrontal cortex	UBERON:0000451	52.84	gold quality
skin of hip	UBERON:0001554	52.70	gold quality
islet of Langerhans	UBERON:0000006	52.49	gold quality
smooth muscle tissue	UBERON:0001135	52.43	gold quality
cerebellum	UBERON:0002037	52.24	gold quality
right hemisphere of cerebellum	UBERON:0014890	51.72	gold quality
muscle of leg	UBERON:0001383	51.21	gold quality
left ovary	UBERON:0002119	51.05	gold quality
gastrocnemius	UBERON:0001388	50.92	gold quality
vermiform appendix	UBERON:0001154	50.80	gold quality
nucleus accumbens	UBERON:0001882	50.60	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	49.61	gold quality
putamen	UBERON:0001874	49.56	gold quality
amygdala	UBERON:0001876	49.55	gold quality
right testis	UBERON:0004534	49.53	gold quality
caudate nucleus	UBERON:0001873	49.43	gold quality
lymph node	UBERON:0000029	49.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.