IL7R-AS1

Summary

IL7R-AS1 (IL7R and SPEF2 antisense RNA 1, HGNC:59028) is a long non-coding RNA gene on chromosome 5p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59028
Approved symbol	IL7R-AS1
Name	IL7R and SPEF2 antisense RNA 1
Location	5p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248969
Ensembl biotype	lncRNA
Entrez	144667556

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000510433, ENST00000736912

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510433 — 4 exons

Exon	Start	End
ENSE00002032333	35678484	35678709
ENSE00002039345	35826846	35827018
ENSE00002069194	35697958	35698035
ENSE00002081203	35683980	35684042

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 61.02.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
islet of Langerhans	UBERON:0000006	61.02	gold quality
lymph node	UBERON:0000029	60.45	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.69	gold quality
vermiform appendix	UBERON:0001154	58.96	gold quality
monocyte	CL:0000576	56.43	gold quality
prefrontal cortex	UBERON:0000451	54.66	gold quality
blood	UBERON:0000178	52.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.89	gold quality
gall bladder	UBERON:0002110	51.53	gold quality
adult mammalian kidney	UBERON:0000082	50.16	gold quality
cortex of kidney	UBERON:0001225	50.15	silver quality
kidney	UBERON:0002113	49.50	gold quality
calcaneal tendon	UBERON:0003701	49.31	silver quality
tonsil	UBERON:0002372	48.47	gold quality
liver	UBERON:0002107	48.14	gold quality
gastrocnemius	UBERON:0001388	46.28	silver quality
granulocyte	CL:0000094	45.71	silver quality
mucosa of stomach	UBERON:0001199	44.77	gold quality
thoracic mammary gland	UBERON:0005200	44.61	gold quality
substantia nigra	UBERON:0002038	44.24	gold quality
body of pancreas	UBERON:0001150	44.13	silver quality
body of uterus	UBERON:0009853	44.12	gold quality
cerebellar hemisphere	UBERON:0002245	43.85	silver quality
endocervix	UBERON:0000458	43.83	gold quality
ascending aorta	UBERON:0001496	43.75	silver quality
heart left ventricle	UBERON:0002084	43.64	gold quality
tibial artery	UBERON:0007610	43.64	silver quality
lung	UBERON:0002048	43.59	silver quality
thoracic aorta	UBERON:0001515	43.48	silver quality
heart	UBERON:0000948	43.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.