INHBA-AS1

Summary

INHBA-AS1 (INHBA antisense RNA 1, HGNC:40303) is a long non-coding RNA gene on chromosome 7p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40303
Approved symbol	INHBA-AS1
Name	INHBA antisense RNA 1
Location	7p14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224116
Ensembl biotype	lncRNA
Entrez	285954
RNAcentral	URS0000CCDF9A — lncRNA, 2992 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000415848, ENST00000420821, ENST00000422822, ENST00000662248, ENST00000662280, ENST00000667639, ENST00000670641

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415848 — 4 exons

Exon	Start	End
ENSE00001646303	41710598	41710782
ENSE00001697415	41693916	41694088
ENSE00001702163	41772896	41772994
ENSE00001775356	41776841	41779388

Expression profiles

Bgee: expression breadth ubiquitous, 142 present calls, max score 73.94.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3579 / max 38.9505, expressed in 84 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
78310	0.3579	84

Top tissues by expression

230 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
nucleus accumbens	UBERON:0001882	73.94	gold quality
amygdala	UBERON:0001876	72.44	gold quality
ganglionic eminence	UBERON:0004023	70.20	gold quality
anterior cingulate cortex	UBERON:0009835	69.99	gold quality
hypothalamus	UBERON:0001898	68.57	gold quality
putamen	UBERON:0001874	68.09	gold quality
Ammon’s horn	UBERON:0001954	68.09	gold quality
caudate nucleus	UBERON:0001873	67.48	gold quality
prefrontal cortex	UBERON:0000451	67.14	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.97	gold quality
tibial artery	UBERON:0007610	66.96	gold quality
popliteal artery	UBERON:0002250	66.94	gold quality
islet of Langerhans	UBERON:0000006	66.00	gold quality
right coronary artery	UBERON:0001625	65.24	gold quality
aorta	UBERON:0000947	64.32	gold quality
cortical plate	UBERON:0005343	64.27	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	64.23	gold quality
forebrain	UBERON:0001890	63.82	gold quality
neocortex	UBERON:0001950	63.51	gold quality
left coronary artery	UBERON:0001626	63.49	gold quality
descending thoracic aorta	UBERON:0002345	63.39	gold quality
cerebral cortex	UBERON:0000956	63.16	gold quality
right frontal lobe	UBERON:0002810	62.95	gold quality
temporal lobe	UBERON:0001871	62.70	gold quality
bone marrow cell	CL:0002092	62.63	silver quality
frontal cortex	UBERON:0001870	62.63	gold quality
ventricular zone	UBERON:0003053	62.37	gold quality
coronary artery	UBERON:0001621	62.36	gold quality
brain	UBERON:0000955	61.40	gold quality
thoracic aorta	UBERON:0001515	61.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.08

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• LncRNA INHBA-AS1 promotes colorectal cancer cell proliferation by sponging miR-422a to increase AKT1 axis. (PMID:33090398)
• Silencing of long noncoding INHBA antisense RNA1 suppresses proliferation, migration, and extracellular matrix deposition in human hypertrophic scar fibroblasts via regulating microRNA-141-3p/myeloid cell leukemia 1 axis. (PMID:33977869)
• Identification of lncRNA-associated competing endogenous RNA networks for occurrence and prognosis of gastric carcinoma. (PMID:34704289)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.