INKA2-AS1

Summary

INKA2-AS1 (INKA2 antisense RNA 1, HGNC:49446) is a long non-coding RNA gene on chromosome 1p13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49446
Approved symbol	INKA2-AS1
Name	INKA2 antisense RNA 1
Location	1p13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227811
Ensembl biotype	lncRNA
Entrez	100506343
RNAcentral	URS000001A4F7 — lncRNA, 2131 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000430373, ENST00000524935, ENST00000658759, ENST00000730712

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430373 — 3 exons

Exon	Start	End
ENSE00001794100	111744375	111744529
ENSE00004059505	111739720	111740098
ENSE00004059507	111746060	111747777

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 81.91.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5722 / max 68.5114, expressed in 275 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
4650	0.2884	130
4649	0.1579	51
4648	0.1259	44

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.91	gold quality
cardiac muscle of right atrium	UBERON:0003379	81.45	gold quality
ileal mucosa	UBERON:0000331	80.24	silver quality
left ventricle myocardium	UBERON:0006566	80.01	gold quality
monocyte	CL:0000576	75.85	gold quality
leukocyte	CL:0000738	74.91	gold quality
stromal cell of endometrium	CL:0002255	74.68	gold quality
cardiac atrium	UBERON:0002081	72.12	gold quality
right atrium auricular region	UBERON:0006631	71.95	gold quality
tibialis anterior	UBERON:0001385	71.79	silver quality
apex of heart	UBERON:0002098	70.54	gold quality
colonic epithelium	UBERON:0000397	69.81	silver quality
ganglionic eminence	UBERON:0004023	69.51	gold quality
epithelial cell of pancreas	CL:0000083	68.40	gold quality
cortical plate	UBERON:0005343	68.23	gold quality
heart left ventricle	UBERON:0002084	68.08	gold quality
tibia	UBERON:0000979	67.77	gold quality
cardiac ventricle	UBERON:0002082	67.63	gold quality
bone marrow cell	CL:0002092	67.45	silver quality
heart	UBERON:0000948	66.75	gold quality
prefrontal cortex	UBERON:0000451	66.61	gold quality
kidney epithelium	UBERON:0004819	65.31	gold quality
ventricular zone	UBERON:0003053	65.14	gold quality
granulocyte	CL:0000094	65.07	gold quality
myocardium	UBERON:0002349	64.54	gold quality
gastrocnemius	UBERON:0001388	64.51	gold quality
muscle of leg	UBERON:0001383	64.43	gold quality
islet of Langerhans	UBERON:0000006	63.01	gold quality
deltoid	UBERON:0001476	61.59	gold quality
frontal cortex	UBERON:0001870	61.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.