INSYN1-AS1

Summary

INSYN1-AS1 (INSYN1 antisense RNA 1, HGNC:51422) is a long non-coding RNA gene on chromosome 15q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51422
Approved symbol	INSYN1-AS1
Name	INSYN1 antisense RNA 1
Location	15q24.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00023459
Ensembl gene	ENSG00000260469
Ensembl biotype	lncRNA
Entrez	101929221
RNAcentral	URS000075BAB7 — lncRNA, 684 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000562031, ENST00000615095, ENST00000663106, ENST00000844239, ENST00000844240, ENST00000844241, ENST00000844242, ENST00000844243, ENST00000844244, ENST00000844245, ENST00000844246, ENST00000844247, ENST00000844248, ENST00000844249

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000562031 — 4 exons

Exon	Start	End
ENSE00002616795	73768753	73768860
ENSE00004270880	73752295	73752396
ENSE00004270884	73769470	73770611
ENSE00004270893	73767789	73768456

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 81.10.

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.10	gold quality
left testis	UBERON:0004533	74.67	gold quality
right testis	UBERON:0004534	73.32	gold quality
tendon of biceps brachii	UBERON:0008188	72.36	silver quality
testis	UBERON:0000473	71.83	gold quality
ganglionic eminence	UBERON:0004023	70.98	gold quality
parotid gland	UBERON:0001831	68.54	gold quality
hypothalamus	UBERON:0001898	67.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	67.64	gold quality
ventricular zone	UBERON:0003053	67.12	gold quality
heart right ventricle	UBERON:0002080	66.56	gold quality
nasal cavity epithelium	UBERON:0005384	64.23	gold quality
biceps brachii	UBERON:0001507	64.08	gold quality
vena cava	UBERON:0004087	63.87	gold quality
substantia nigra	UBERON:0002038	63.73	gold quality
cortical plate	UBERON:0005343	63.70	gold quality
cerebellar vermis	UBERON:0004720	63.22	gold quality
adult mammalian kidney	UBERON:0000082	62.90	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	62.75	gold quality
midbrain	UBERON:0001891	62.68	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.28	gold quality
prefrontal cortex	UBERON:0000451	62.24	gold quality
cortex of kidney	UBERON:0001225	61.82	gold quality
medial globus pallidus	UBERON:0002477	61.76	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.36	gold quality
lower esophagus mucosa	UBERON:0035834	61.27	gold quality
skeletal muscle tissue	UBERON:0001134	60.98	gold quality
body of tongue	UBERON:0011876	60.70	gold quality
globus pallidus	UBERON:0001875	60.58	gold quality
cerebellar hemisphere	UBERON:0002245	59.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.