INTS6-AS1

Summary

INTS6-AS1 (INTS6 antisense RNA 1, HGNC:42691) is a long non-coding RNA gene on chromosome 13q14.3.

Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting.

Source: NCBI Gene 100507398 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42691
Approved symbol	INTS6-AS1
Name	INTS6 antisense RNA 1
Location	13q14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236778
Ensembl biotype	lncRNA
Entrez	100507398
RNAcentral	URS000075B759 — lncRNA, 810 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000434512, ENST00000593429, ENST00000593672, ENST00000593709, ENST00000593928, ENST00000594358, ENST00000594488, ENST00000594604, ENST00000594959, ENST00000595424, ENST00000595435, ENST00000595905, ENST00000595997, ENST00000596050, ENST00000596180, ENST00000596303, ENST00000596904, ENST00000597745, ENST00000598864, ENST00000598905, ENST00000599315, ENST00000600477, ENST00000601034, ENST00000601318, ENST00000601572, ENST00000602089, ENST00000608520, ENST00000610018, ENST00000610618, ENST00000626895, ENST00000629988, ENST00000630116, ENST00000657609, ENST00000665862, ENST00000670302, ENST00000771230, ENST00000771231, ENST00000771232, ENST00000771233, ENST00000771234, ENST00000771235, ENST00000771236

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434512 — 2 exons

Exon	Start	End
ENSE00001693246	51549710	51549992
ENSE00001771505	51454147	51454329

Expression profiles

Bgee: expression breadth ubiquitous, 184 present calls, max score 87.00.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.3365 / max 36.2585, expressed in 1161 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
135196	2.3153	1154
135195	0.0212	7

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	87.00	gold quality
left testis	UBERON:0004533	86.63	gold quality
right uterine tube	UBERON:0001302	86.39	gold quality
testis	UBERON:0000473	83.81	gold quality
adenohypophysis	UBERON:0002196	81.83	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.98	gold quality
body of pancreas	UBERON:0001150	80.90	gold quality
pituitary gland	UBERON:0000007	80.88	gold quality
left ovary	UBERON:0002119	80.79	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.65	gold quality
sperm	CL:0000019	80.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	79.98	gold quality
right ovary	UBERON:0002118	79.58	gold quality
cerebellar hemisphere	UBERON:0002245	79.27	gold quality
right lobe of thyroid gland	UBERON:0001119	79.21	gold quality
calcaneal tendon	UBERON:0003701	79.20	gold quality
cerebellar cortex	UBERON:0002129	79.03	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	78.90	gold quality
left lobe of thyroid gland	UBERON:0001120	78.87	gold quality
pancreas	UBERON:0001264	78.69	gold quality
right adrenal gland	UBERON:0001233	78.62	gold quality
tibial nerve	UBERON:0001323	78.54	gold quality
spleen	UBERON:0002106	78.28	gold quality
thyroid gland	UBERON:0002046	78.13	gold quality
body of uterus	UBERON:0009853	77.99	gold quality
monocyte	CL:0000576	77.82	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.80	gold quality
right adrenal gland cortex	UBERON:0035827	77.78	gold quality
leukocyte	CL:0000738	77.77	gold quality
left adrenal gland cortex	UBERON:0035825	77.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.