IQSEC3-AS1

Summary

IQSEC3-AS1 (IQSEC3 antisense RNA 1, HGNC:56002) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56002
Approved symbol	IQSEC3-AS1
Name	IQSEC3 antisense RNA 1
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256540
Ensembl biotype	lncRNA
Entrez	105369592
RNAcentral	URS00026A2510 — lncRNA, 3429 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000537295, ENST00000537961, ENST00000540136, ENST00000755015, ENST00000755016, ENST00000755017, ENST00000755018, ENST00000755019, ENST00000755020, ENST00000755069

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000537295 — 3 exons

Exon	Start	End
ENSE00002249988	167620	167707
ENSE00004103553	166856	167501
ENSE00004103556	182068	182499

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 85.24.

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.24	gold quality
placenta	UBERON:0001987	83.09	gold quality
apex of heart	UBERON:0002098	83.01	gold quality
right hemisphere of cerebellum	UBERON:0014890	77.86	gold quality
cerebellar cortex	UBERON:0002129	77.12	gold quality
cerebellar hemisphere	UBERON:0002245	77.11	gold quality
cerebellum	UBERON:0002037	76.96	gold quality
heart left ventricle	UBERON:0002084	73.50	gold quality
bone marrow cell	CL:0002092	72.11	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.12	gold quality
right lung	UBERON:0002167	70.64	gold quality
skeletal muscle tissue	UBERON:0001134	69.87	gold quality
colonic epithelium	UBERON:0000397	65.80	silver quality
islet of Langerhans	UBERON:0000006	65.31	gold quality
upper lobe of left lung	UBERON:0008952	65.00	gold quality
heart	UBERON:0000948	64.82	gold quality
lung	UBERON:0002048	64.46	gold quality
superior frontal gyrus	UBERON:0002661	64.25	gold quality
primary visual cortex	UBERON:0002436	64.21	gold quality
muscle of leg	UBERON:0001383	63.40	gold quality
smooth muscle tissue	UBERON:0001135	63.20	gold quality
right frontal lobe	UBERON:0002810	63.14	gold quality
right uterine tube	UBERON:0001302	63.06	gold quality
brain	UBERON:0000955	62.58	gold quality
anterior cingulate cortex	UBERON:0009835	62.52	gold quality
hypothalamus	UBERON:0001898	62.19	gold quality
gastrocnemius	UBERON:0001388	61.92	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.10	gold quality
putamen	UBERON:0001874	60.95	gold quality
cerebral cortex	UBERON:0000956	60.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.