IQSEC3-AS2

Summary

IQSEC3-AS2 (IQSEC3 antisense RNA 2, HGNC:56741) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56741
Approved symbol	IQSEC3-AS2
Name	IQSEC3 antisense RNA 2
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC026369.3
Ensembl gene	ENSG00000256948
Ensembl biotype	lncRNA
Entrez	105369593
RNAcentral	URS0002347609 — lncRNA, 497 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000540226

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000540226 — 2 exons

Exon	Start	End
ENSE00004091320	111619	111964
ENSE00004091321	106509	106877

Expression profiles

Bgee: expression breadth ubiquitous, 102 present calls, max score 84.50.

Top tissues by expression

102 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lung	UBERON:0002167	84.50	gold quality
monocyte	CL:0000576	80.07	gold quality
leukocyte	CL:0000738	79.75	gold quality
upper lobe of left lung	UBERON:0008952	77.27	gold quality
lung	UBERON:0002048	76.99	gold quality
bone marrow cell	CL:0002092	76.65	gold quality
granulocyte	CL:0000094	73.57	gold quality
bone marrow	UBERON:0002371	71.19	gold quality
lymph node	UBERON:0000029	67.97	gold quality
skeletal muscle tissue	UBERON:0001134	64.34	silver quality
tonsil	UBERON:0002372	63.36	gold quality
placenta	UBERON:0001987	62.37	gold quality
liver	UBERON:0002107	61.24	gold quality
vermiform appendix	UBERON:0001154	61.15	gold quality
blood	UBERON:0000178	58.41	gold quality
right adrenal gland cortex	UBERON:0035827	57.71	gold quality
smooth muscle tissue	UBERON:0001135	57.63	gold quality
right lobe of liver	UBERON:0001114	57.31	gold quality
gall bladder	UBERON:0002110	56.11	gold quality
descending thoracic aorta	UBERON:0002345	55.83	gold quality
right coronary artery	UBERON:0001625	55.68	gold quality
left coronary artery	UBERON:0001626	54.33	gold quality
right ovary	UBERON:0002118	53.82	gold quality
subcutaneous adipose tissue	UBERON:0002190	53.50	gold quality
adipose tissue	UBERON:0001013	53.18	gold quality
omental fat pad	UBERON:0010414	52.81	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.67	gold quality
cortex of kidney	UBERON:0001225	52.60	gold quality
myometrium	UBERON:0001296	51.91	gold quality
spleen	UBERON:0002106	51.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.