IQSEC3-AS3

Summary

IQSEC3-AS3 (IQSEC3 antisense RNA 3, HGNC:58418) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58418
Approved symbol	IQSEC3-AS3
Name	IQSEC3 antisense RNA 3
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249695
Ensembl biotype	lncRNA
Entrez	574538

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000505893, ENST00000508953

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505893 — 10 exons

Exon	Start	End
ENSE00002019139	138300	138452
ENSE00002043274	138551	138644
ENSE00002044357	149079	149169
ENSE00002047421	137411	137627
ENSE00002053030	144309	144569
ENSE00002054446	141334	142633
ENSE00002067883	140240	140370
ENSE00002068750	140648	140803
ENSE00002082134	140912	141244
ENSE00002087488	143239	143409

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 67.03.

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortex of kidney	UBERON:0001225	67.03	gold quality
metanephros cortex	UBERON:0010533	65.66	gold quality
small intestine Peyer’s patch	UBERON:0003454	61.44	gold quality
right hemisphere of cerebellum	UBERON:0014890	59.58	gold quality
cerebellum	UBERON:0002037	58.80	gold quality
cerebellar hemisphere	UBERON:0002245	58.80	gold quality
cerebellar cortex	UBERON:0002129	58.77	gold quality
islet of Langerhans	UBERON:0000006	58.09	gold quality
right uterine tube	UBERON:0001302	57.96	gold quality
ganglionic eminence	UBERON:0004023	57.40	silver quality
kidney	UBERON:0002113	56.78	gold quality
pituitary gland	UBERON:0000007	56.59	gold quality
cortical plate	UBERON:0005343	56.14	silver quality
adenohypophysis	UBERON:0002196	54.79	gold quality
myometrium	UBERON:0001296	54.62	gold quality
adult mammalian kidney	UBERON:0000082	54.02	gold quality
urinary bladder	UBERON:0001255	53.70	gold quality
prefrontal cortex	UBERON:0000451	52.56	gold quality
Ammon’s horn	UBERON:0001954	50.07	gold quality
frontal cortex	UBERON:0001870	49.72	gold quality
left adrenal gland cortex	UBERON:0035825	49.72	gold quality
muscle of leg	UBERON:0001383	49.61	silver quality
endometrium	UBERON:0001295	49.53	gold quality
brain	UBERON:0000955	49.48	gold quality
lymph node	UBERON:0000029	49.40	silver quality
fallopian tube	UBERON:0003889	49.15	gold quality
cerebral cortex	UBERON:0000956	48.32	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.25	gold quality
hypothalamus	UBERON:0001898	48.22	gold quality
primary visual cortex	UBERON:0002436	47.53	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.