IRF2-DT

Summary

IRF2-DT (IRF2 divergent transcript, HGNC:54871) is a long non-coding RNA gene on chromosome 4q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54871
Approved symbol	IRF2-DT
Name	IRF2 divergent transcript
Location	4q35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000271646
Ensembl biotype	lncRNA
Entrez	117134601
RNAcentral	URS00004FD093 — lncRNA, 2503 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000605834, ENST00000667665, ENST00000696854, ENST00000696855, ENST00000717452

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000605834 — 1 exons

Exon	Start	End
ENSE00004152901	184474666	184477304

Expression profiles

Bgee: expression breadth ubiquitous, 166 present calls, max score 74.05.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.4611 / max 433.9727, expressed in 1158 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
50836	3.4611	1158

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	74.05	gold quality
bone marrow cell	CL:0002092	73.46	gold quality
oviduct epithelium	UBERON:0004804	72.71	gold quality
left ventricle myocardium	UBERON:0006566	72.23	gold quality
monocyte	CL:0000576	72.21	gold quality
leukocyte	CL:0000738	72.14	gold quality
cardiac muscle of right atrium	UBERON:0003379	71.98	gold quality
left adrenal gland cortex	UBERON:0035825	71.89	gold quality
left adrenal gland	UBERON:0001234	71.85	gold quality
right adrenal gland	UBERON:0001233	71.24	gold quality
granulocyte	CL:0000094	70.69	gold quality
adrenal cortex	UBERON:0001235	70.66	gold quality
vermiform appendix	UBERON:0001154	70.30	gold quality
right adrenal gland cortex	UBERON:0035827	70.25	gold quality
mucosa of stomach	UBERON:0001199	70.23	gold quality
lymph node	UBERON:0000029	70.21	gold quality
spleen	UBERON:0002106	70.12	gold quality
right uterine tube	UBERON:0001302	70.11	gold quality
cerebellar vermis	UBERON:0004720	70.03	gold quality
adrenal gland	UBERON:0002369	69.85	gold quality
popliteal artery	UBERON:0002250	69.34	gold quality
tibial artery	UBERON:0007610	69.34	gold quality
left coronary artery	UBERON:0001626	69.17	gold quality
right lobe of liver	UBERON:0001114	68.96	gold quality
gastrocnemius	UBERON:0001388	68.95	gold quality
fallopian tube	UBERON:0003889	68.90	gold quality
endothelial cell	CL:0000115	68.75	gold quality
muscle of leg	UBERON:0001383	68.75	gold quality
descending thoracic aorta	UBERON:0002345	68.75	gold quality
tibial nerve	UBERON:0001323	68.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.41

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.