IRX3-AS1

Summary

IRX3-AS1 (IRX3 antisense RNA 1, HGNC:58975) is a long non-coding RNA gene on chromosome 16q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58975
Approved symbol	IRX3-AS1
Name	IRX3 antisense RNA 1
Location	16q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.403
Ensembl gene	ENSG00000287885
Ensembl biotype	lncRNA
Entrez	144511952

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000616682, ENST00000637770, ENST00000663832, ENST00000717486, ENST00000717487, ENST00000720695, ENST00000720696, ENST00000720697, ENST00000720698, ENST00000720699, ENST00000720700, ENST00000720761, ENST00000720762, ENST00000720763

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000616682 — 2 exons

Exon	Start	End
ENSE00004032646	54290207	54292422
ENSE00004039837	54285239	54285365

Expression profiles

Bgee: expression breadth broad, 42 present calls, max score 65.42.

Top tissues by expression

42 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	65.42	gold quality
prefrontal cortex	UBERON:0000451	53.86	gold quality
muscle of leg	UBERON:0001383	51.10	gold quality
gastrocnemius	UBERON:0001388	50.66	gold quality
blood	UBERON:0000178	50.52	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	47.65	gold quality
islet of Langerhans	UBERON:0000006	46.84	silver quality
monocyte	CL:0000576	46.49	silver quality
thoracic mammary gland	UBERON:0005200	44.47	gold quality
kidney	UBERON:0002113	42.87	silver quality
left lobe of thyroid gland	UBERON:0001120	42.59	gold quality
fallopian tube	UBERON:0003889	42.47	silver quality
tibial artery	UBERON:0007610	42.34	silver quality
heart left ventricle	UBERON:0002084	42.17	silver quality
Ammon’s horn	UBERON:0001954	41.82	silver quality
thyroid gland	UBERON:0002046	41.74	silver quality
skin of abdomen	UBERON:0001416	41.70	silver quality
omental fat pad	UBERON:0010414	41.64	silver quality
esophagus	UBERON:0001043	41.50	silver quality
putamen	UBERON:0001874	41.50	silver quality
zone of skin	UBERON:0000014	41.41	silver quality
ectocervix	UBERON:0012249	41.21	silver quality
adipose tissue	UBERON:0001013	41.10	silver quality
body of stomach	UBERON:0001161	41.08	silver quality
stomach	UBERON:0000945	41.02	silver quality
skin of leg	UBERON:0001511	41.02	silver quality
subcutaneous adipose tissue	UBERON:0002190	41.02	silver quality
esophagus mucosa	UBERON:0002469	40.80	silver quality
fundus of stomach	UBERON:0001160	39.85	silver quality
left coronary artery	UBERON:0001626	39.24	silver quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.