IRX4-AS1

Summary

IRX4-AS1 (IRX4 antisense RNA 1, HGNC:40305) is a long non-coding RNA gene on chromosome 5p15.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40305
Approved symbol	IRX4-AS1
Name	IRX4 antisense RNA 1
Location	5p15.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249116
Ensembl biotype	lncRNA
Entrez	101929056
RNAcentral	URS00026A1E45 — lncRNA, 384 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000506335, ENST00000692531, ENST00000693594, ENST00000755142, ENST00000755143, ENST00000755144

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506335 — 2 exons

Exon	Start	End
ENSE00004103849	1884480	1884758
ENSE00004103853	1883816	1884220

Expression profiles

Bgee: expression breadth broad, 72 present calls, max score 87.82.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0561 / max 3.6340, expressed in 34 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55584	0.0561	34

Top tissues by expression

72 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
heart left ventricle	UBERON:0002084	87.82	gold quality
apex of heart	UBERON:0002098	86.71	gold quality
hindlimb stylopod muscle	UBERON:0004252	80.16	gold quality
heart	UBERON:0000948	79.57	gold quality
muscle of leg	UBERON:0001383	75.90	gold quality
gastrocnemius	UBERON:0001388	74.79	gold quality
skeletal muscle tissue	UBERON:0001134	72.07	gold quality
left ovary	UBERON:0002119	70.70	gold quality
skin of abdomen	UBERON:0001416	69.36	gold quality
zone of skin	UBERON:0000014	67.82	gold quality
skin of leg	UBERON:0001511	66.91	gold quality
esophagus mucosa	UBERON:0002469	65.04	gold quality
lower esophagus mucosa	UBERON:0035834	64.48	gold quality
multicellular organism	UBERON:0000468	64.17	gold quality
lymph node	UBERON:0000029	63.89	gold quality
esophagus	UBERON:0001043	63.54	gold quality
ectocervix	UBERON:0012249	63.14	gold quality
minor salivary gland	UBERON:0001830	61.81	gold quality
vagina	UBERON:0000996	61.27	gold quality
prostate gland	UBERON:0002367	60.06	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.78	gold quality
ovary	UBERON:0000992	57.00	gold quality
liver	UBERON:0002107	56.71	gold quality
islet of Langerhans	UBERON:0000006	55.82	gold quality
thoracic mammary gland	UBERON:0005200	54.79	gold quality
small intestine Peyer’s patch	UBERON:0003454	54.41	gold quality
placenta	UBERON:0001987	54.05	gold quality
adult mammalian kidney	UBERON:0000082	53.86	gold quality
blood	UBERON:0000178	52.09	gold quality
monocyte	CL:0000576	51.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.84

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.