ISM1-AS1

Summary

ISM1-AS1 (ISM1 antisense RNA 1, HGNC:44313) is a long non-coding RNA gene on chromosome 20p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44313
Approved symbol	ISM1-AS1
Name	ISM1 antisense RNA 1
Location	20p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226263
Ensembl biotype	lncRNA
Entrez	100505536
RNAcentral	URS000075AFFD — lncRNA, 1061 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000431407, ENST00000802912

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431407 — 3 exons

Exon	Start	End
ENSE00001648091	13238984	13239104
ENSE00001715223	13239453	13239674
ENSE00001762168	13237801	13238109

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 96.53.

Top tissues by expression

218 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.53	gold quality
sperm	CL:0000019	72.48	silver quality
left testis	UBERON:0004533	63.38	gold quality
right testis	UBERON:0004534	61.78	gold quality
testis	UBERON:0000473	61.21	gold quality
tendon of biceps brachii	UBERON:0008188	59.13	gold quality
popliteal artery	UBERON:0002250	58.11	gold quality
tibial artery	UBERON:0007610	58.01	gold quality
calcaneal tendon	UBERON:0003701	57.98	gold quality
aorta	UBERON:0000947	56.67	gold quality
ascending aorta	UBERON:0001496	55.08	gold quality
monocyte	CL:0000576	55.02	silver quality
thoracic aorta	UBERON:0001515	54.90	gold quality
right coronary artery	UBERON:0001625	54.70	gold quality
body of pancreas	UBERON:0001150	53.14	gold quality
left lobe of thyroid gland	UBERON:0001120	53.13	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.79	gold quality
thyroid gland	UBERON:0002046	52.78	gold quality
pancreas	UBERON:0001264	52.56	gold quality
tendon	UBERON:0000043	52.52	gold quality
skin of abdomen	UBERON:0001416	52.47	gold quality
skin of leg	UBERON:0001511	52.23	gold quality
islet of Langerhans	UBERON:0000006	52.05	gold quality
right lobe of thyroid gland	UBERON:0001119	51.95	gold quality
gall bladder	UBERON:0002110	51.88	gold quality
zone of skin	UBERON:0000014	50.81	gold quality
lower esophagus mucosa	UBERON:0035834	50.66	gold quality
cerebellar vermis	UBERON:0004720	50.58	gold quality
tonsil	UBERON:0002372	50.43	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	50.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.