ISOC1-AS1

Summary

ISOC1-AS1 (ISOC1 antisense RNA 1, HGNC:59129) is a long non-coding RNA gene on chromosome 5q23.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:59129
Approved symbol	ISOC1-AS1
Name	ISOC1 antisense RNA 1
Location	5q23.3
Locus type	RNA, long non-coding
Status	Approved
Entrez	124901060

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000364658 (5:129097615 A>G), RS1001941244 (5:129094451 G>A), RS1001995036 (5:129094256 C>T), RS1002474655 (5:129094576 C>G,T), RS1002757799 (5:129095541 A>C), RS1004327997 (5:129096742 C>T), RS1004402271 (5:129097448 A>G), RS1004457628 (5:129097065 T>A), RS1004579174 (5:129092692 T>G), RS1004741132 (5:129095827 A>C), RS1004792004 (5:129095582 C>T), RS1006466035 (5:129094475 G>A,C), RS1006702951 (5:129094758 CG>C,CGG), RS1006748742 (5:129093596 C>G), RS1008363136 (5:129098113 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.