ITFG2-AS1

Summary

ITFG2-AS1 (ITFG2 antisense RNA 1, HGNC:53128) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53128
Approved symbol	ITFG2-AS1
Name	ITFG2 antisense RNA 1
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258325
Ensembl biotype	lncRNA
Entrez	283440
RNAcentral	URS0000BC45F8 — lncRNA, 652 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 43 — 43 lncRNA

ENST00000501371, ENST00000536497, ENST00000540093, ENST00000540428, ENST00000541673, ENST00000544517, ENST00000545526, ENST00000547042, ENST00000547794, ENST00000547834, ENST00000552469, ENST00000636122, ENST00000715729, ENST00000715730, ENST00000715731, ENST00000715732, ENST00000839340, ENST00000839341, ENST00000839342, ENST00000839343, ENST00000839344, ENST00000839345, ENST00000839346, ENST00000839347, ENST00000839348, ENST00000839349, ENST00000839350, ENST00000839351, ENST00000839352, ENST00000839353, ENST00000839354, ENST00000839355, ENST00000839356, ENST00000839357, ENST00000839358, ENST00000839359, ENST00000839360, ENST00000839361, ENST00000839362, ENST00000839363, ENST00000839364, ENST00000839365, ENST00000839366

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501371 — 4 exons

Exon	Start	End
ENSE00001963022	2691069	2691118
ENSE00001967490	2690807	2690979
ENSE00001968098	2690140	2690210
ENSE00001970846	2676001	2677897

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 89.12.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.6044 / max 86.1546, expressed in 151 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
128967	2.0009	1105
128966	1.4828	825
128960	0.3291	98
128959	0.2753	87

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.73	gold quality
left testis	UBERON:0004533	80.02	gold quality
testis	UBERON:0000473	80.00	gold quality
right testis	UBERON:0004534	79.81	gold quality
ventricular zone	UBERON:0003053	73.83	gold quality
muscle of leg	UBERON:0001383	72.15	gold quality
apex of heart	UBERON:0002098	71.85	gold quality
gastrocnemius	UBERON:0001388	71.61	gold quality
sural nerve	UBERON:0015488	71.42	gold quality
cortical plate	UBERON:0005343	71.38	gold quality
skeletal muscle tissue	UBERON:0001134	71.23	gold quality
colonic epithelium	UBERON:0000397	70.91	silver quality
ganglionic eminence	UBERON:0004023	69.34	gold quality
calcaneal tendon	UBERON:0003701	69.26	gold quality
bone marrow cell	CL:0002092	69.10	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	68.46	gold quality
lymph node	UBERON:0000029	67.69	gold quality
mucosa of transverse colon	UBERON:0004991	67.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.38	gold quality
leukocyte	CL:0000738	67.37	gold quality
fundus of stomach	UBERON:0001160	67.35	gold quality
monocyte	CL:0000576	67.31	gold quality
right uterine tube	UBERON:0001302	66.95	gold quality
prefrontal cortex	UBERON:0000451	66.69	gold quality
corpus callosum	UBERON:0002336	66.35	gold quality
saliva-secreting gland	UBERON:0001044	66.25	gold quality
minor salivary gland	UBERON:0001830	65.91	gold quality
vermiform appendix	UBERON:0001154	65.81	gold quality
left adrenal gland cortex	UBERON:0035825	65.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.