ITGA6-AS1

Summary

ITGA6-AS1 (ITGA6 and PDK1 antisense RNA 1, HGNC:40308) is a long non-coding RNA gene on chromosome 2q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40308
Approved symbol	ITGA6-AS1
Name	ITGA6 and PDK1 antisense RNA 1
Location	2q31.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	lncIHAT, AC078883.3
Ensembl gene	ENSG00000232788
Ensembl biotype	lncRNA
Entrez	101929947
RNAcentral	URS00000137A7 — lncRNA, 512 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000416080, ENST00000417539, ENST00000436922, ENST00000442417, ENST00000444919, ENST00000450443, ENST00000458314, ENST00000715602, ENST00000830319, ENST00000830320, ENST00000830321, ENST00000830322, ENST00000830323

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416080 — 3 exons

Exon	Start	End
ENSE00001594719	172509603	172509813
ENSE00001689301	172512334	172512510
ENSE00001773604	172509029	172509294

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 86.02.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	86.02	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.55	gold quality
bone marrow cell	CL:0002092	80.71	gold quality
monocyte	CL:0000576	79.82	gold quality
leukocyte	CL:0000738	79.35	gold quality
blood	UBERON:0000178	78.13	gold quality
sural nerve	UBERON:0015488	77.57	gold quality
tonsil	UBERON:0002372	76.65	gold quality
bone marrow	UBERON:0002371	74.99	gold quality
corpus callosum	UBERON:0002336	72.78	gold quality
spleen	UBERON:0002106	72.70	gold quality
granulocyte	CL:0000094	72.17	gold quality
lymph node	UBERON:0000029	70.88	gold quality
calcaneal tendon	UBERON:0003701	70.87	gold quality
mucosa of transverse colon	UBERON:0004991	69.32	gold quality
ganglionic eminence	UBERON:0004023	66.70	gold quality
small intestine	UBERON:0002108	65.10	gold quality
minor salivary gland	UBERON:0001830	64.70	gold quality
saliva-secreting gland	UBERON:0001044	64.69	gold quality
small intestine Peyer’s patch	UBERON:0003454	64.68	gold quality
duodenum	UBERON:0002114	64.52	gold quality
metanephros cortex	UBERON:0010533	64.31	gold quality
skeletal muscle tissue	UBERON:0001134	64.04	gold quality
skin of abdomen	UBERON:0001416	64.00	gold quality
muscle tissue	UBERON:0002385	64.00	gold quality
zone of skin	UBERON:0000014	63.98	gold quality
skin of leg	UBERON:0001511	63.92	gold quality
kidney	UBERON:0002113	63.90	gold quality
cortex of kidney	UBERON:0001225	63.84	gold quality
placenta	UBERON:0001987	63.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.35

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.