ITGAL-AS1

Summary

ITGAL-AS1 (ITGAL antisense RNA 1, HGNC:56737) is a long non-coding RNA gene on chromosome 16p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56737
Approved symbol	ITGAL-AS1
Name	ITGAL antisense RNA 1
Location	16p11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-279C4.1
Ensembl gene	ENSG00000261332
Ensembl biotype	lncRNA
Entrez	128667228
RNAcentral	URS00026A26EB — lncRNA, 913 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000563751

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000563751 — 2 exons

Exon	Start	End
ENSE00002581588	30498766	30499151
ENSE00002585723	30499364	30499554

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 79.69.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.69	silver quality
sural nerve	UBERON:0015488	73.52	silver quality
right adrenal gland cortex	UBERON:0035827	72.54	gold quality
right adrenal gland	UBERON:0001233	71.77	gold quality
left adrenal gland	UBERON:0001234	70.85	gold quality
adrenal gland	UBERON:0002369	69.43	gold quality
left adrenal gland cortex	UBERON:0035825	69.36	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.03	gold quality
bone marrow cell	CL:0002092	66.84	silver quality
bone marrow	UBERON:0002371	62.53	gold quality
monocyte	CL:0000576	62.40	gold quality
cerebellum	UBERON:0002037	61.95	gold quality
cerebellar cortex	UBERON:0002129	61.76	gold quality
cerebellar hemisphere	UBERON:0002245	61.56	gold quality
blood	UBERON:0000178	61.22	gold quality
skeletal muscle tissue	UBERON:0001134	60.80	gold quality
right hemisphere of cerebellum	UBERON:0014890	60.45	gold quality
granulocyte	CL:0000094	59.27	gold quality
kidney	UBERON:0002113	58.17	gold quality
right atrium auricular region	UBERON:0006631	58.16	gold quality
adult mammalian kidney	UBERON:0000082	57.84	gold quality
islet of Langerhans	UBERON:0000006	56.07	gold quality
muscle of leg	UBERON:0001383	56.06	gold quality
cortex of kidney	UBERON:0001225	55.83	gold quality
prefrontal cortex	UBERON:0000451	54.79	gold quality
pituitary gland	UBERON:0000007	54.64	gold quality
tonsil	UBERON:0002372	54.55	gold quality
gastrocnemius	UBERON:0001388	54.52	gold quality
heart	UBERON:0000948	54.24	gold quality
duodenum	UBERON:0002114	54.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.