ITGB1-DT

Summary

ITGB1-DT (ITGB1 divergent transcript, HGNC:53718) is a long non-coding RNA gene on chromosome 10p11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53718
Approved symbol	ITGB1-DT
Name	ITGB1 divergent transcript
Location	10p11.22
Locus type	RNA, long non-coding
Status	Approved
Aliases	LincIN
Ensembl gene	ENSG00000229656
Ensembl biotype	lncRNA
Entrez	101929475
RNAcentral	URS00009EC30A — lncRNA, 1031 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 38 — 38 lncRNA

ENST00000414157, ENST00000450890, ENST00000659846, ENST00000666298, ENST00000688627, ENST00000691671, ENST00000700951, ENST00000821378, ENST00000821379, ENST00000821380, ENST00000821381, ENST00000821382, ENST00000821383, ENST00000821384, ENST00000821385, ENST00000821386, ENST00000821387, ENST00000821388, ENST00000821389, ENST00000821390, ENST00000821391, ENST00000821392, ENST00000821393, ENST00000821394, ENST00000821395, ENST00000821396, ENST00000821397, ENST00000821398, ENST00000821399, ENST00000821400, ENST00000821401, ENST00000821402, ENST00000821403, ENST00000821404, ENST00000821405, ENST00000821406, ENST00000821407, ENST00000821408

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414157 — 3 exons

Exon	Start	End
ENSE00003932506	32985623	32985762
ENSE00004228142	33081342	33082102
ENSE00004228165	32982547	32982685

Expression profiles

Bgee: expression breadth ubiquitous, 145 present calls, max score 82.78.

FANTOM5 (CAGE): breadth broad, TPM avg 0.3643 / max 16.1639, expressed in 207 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
104643	0.2535	153
104637	0.1108	38

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
epithelial cell of pancreas	CL:0000083	82.78	silver quality
pancreatic ductal cell	CL:0002079	80.44	silver quality
islet of Langerhans	UBERON:0000006	76.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.79	silver quality
gall bladder	UBERON:0002110	68.69	gold quality
colonic epithelium	UBERON:0000397	65.77	silver quality
ventricular zone	UBERON:0003053	65.74	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.19	gold quality
cortical plate	UBERON:0005343	63.61	gold quality
ganglionic eminence	UBERON:0004023	62.80	gold quality
stromal cell of endometrium	CL:0002255	62.08	gold quality
pancreas	UBERON:0001264	60.63	gold quality
tibialis anterior	UBERON:0001385	60.13	silver quality
ileal mucosa	UBERON:0000331	59.58	silver quality
right lobe of liver	UBERON:0001114	58.85	gold quality
sperm	CL:0000019	58.75	gold quality
tendon of biceps brachii	UBERON:0008188	56.91	gold quality
deltoid	UBERON:0001476	56.88	gold quality
heart left ventricle	UBERON:0002084	56.80	gold quality
liver	UBERON:0002107	56.45	gold quality
cardiac ventricle	UBERON:0002082	56.23	gold quality
myocardium	UBERON:0002349	55.85	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
monocyte	CL:0000576	53.34	silver quality
heart	UBERON:0000948	53.13	gold quality
endothelial cell	CL:0000115	52.60	gold quality
granulocyte	CL:0000094	51.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.