ITGB5-AS1

Summary

ITGB5-AS1 (ITGB5 antisense RNA 1, HGNC:40309) is a long non-coding RNA gene on chromosome 3q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40309
Approved symbol	ITGB5-AS1
Name	ITGB5 antisense RNA 1
Location	3q21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000244286
Ensembl biotype	lncRNA
Entrez	100873992
RNAcentral	URS000011D57F — lncRNA, 460 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000495917

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000495917 — 2 exons

Exon	Start	End
ENSE00001821751	124781155	124781328
ENSE00001940240	124787472	124787757

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 68.25.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
stromal cell of endometrium	CL:0002255	68.25	gold quality
ventricular zone	UBERON:0003053	67.71	gold quality
colonic epithelium	UBERON:0000397	67.63	silver quality
calcaneal tendon	UBERON:0003701	63.57	gold quality
monocyte	CL:0000576	63.37	gold quality
skeletal muscle tissue	UBERON:0001134	61.24	gold quality
corpus callosum	UBERON:0002336	59.78	gold quality
liver	UBERON:0002107	58.62	gold quality
subcutaneous adipose tissue	UBERON:0002190	58.29	gold quality
skin of leg	UBERON:0001511	58.09	gold quality
popliteal artery	UBERON:0002250	56.95	gold quality
tonsil	UBERON:0002372	56.95	silver quality
zone of skin	UBERON:0000014	56.94	gold quality
tibial artery	UBERON:0007610	56.87	gold quality
adipose tissue	UBERON:0001013	55.49	gold quality
left coronary artery	UBERON:0001626	55.36	gold quality
ascending aorta	UBERON:0001496	55.24	gold quality
islet of Langerhans	UBERON:0000006	55.19	gold quality
thoracic aorta	UBERON:0001515	55.08	gold quality
muscle of leg	UBERON:0001383	54.87	gold quality
skin of abdomen	UBERON:0001416	54.84	gold quality
myometrium	UBERON:0001296	54.75	gold quality
placenta	UBERON:0001987	54.42	gold quality
gastrocnemius	UBERON:0001388	54.11	gold quality
gall bladder	UBERON:0002110	54.03	gold quality
descending thoracic aorta	UBERON:0002345	54.03	gold quality
blood	UBERON:0000178	53.85	gold quality
vagina	UBERON:0000996	53.48	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.36	gold quality
rectum	UBERON:0001052	53.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.