ITIH4-AS1

Summary

ITIH4-AS1 (ITIH4 antisense RNA 1, HGNC:40310) is a long non-coding RNA gene on chromosome 3p21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40310
Approved symbol	ITIH4-AS1
Name	ITIH4 antisense RNA 1
Location	3p21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239799
Ensembl biotype	lncRNA
Entrez	100873993
RNAcentral	URS00000CF7F0 — lncRNA, 395 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000478366

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000478366 — 3 exons

Exon	Start	End
ENSE00001825587	52825205	52825314
ENSE00001930469	52823935	52823993
ENSE00001952516	52824112	52824337

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 93.51.

Top tissues by expression

115 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.51	gold quality
right lobe of liver	UBERON:0001114	90.36	gold quality
liver	UBERON:0002107	85.41	gold quality
skeletal muscle tissue	UBERON:0001134	76.77	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.32	gold quality
granulocyte	CL:0000094	70.93	gold quality
muscle of leg	UBERON:0001383	70.06	gold quality
popliteal artery	UBERON:0002250	69.62	gold quality
tibial artery	UBERON:0007610	69.60	gold quality
gastrocnemius	UBERON:0001388	69.00	gold quality
right coronary artery	UBERON:0001625	68.93	gold quality
left coronary artery	UBERON:0001626	65.83	gold quality
monocyte	CL:0000576	63.77	gold quality
stromal cell of endometrium	CL:0002255	63.44	gold quality
bone marrow cell	CL:0002092	62.94	silver quality
bone marrow	UBERON:0002371	62.29	gold quality
primary visual cortex	UBERON:0002436	61.73	gold quality
mucosa of stomach	UBERON:0001199	61.52	gold quality
blood	UBERON:0000178	61.44	gold quality
body of pancreas	UBERON:0001150	61.39	gold quality
pancreas	UBERON:0001264	61.23	gold quality
tonsil	UBERON:0002372	60.75	silver quality
descending thoracic aorta	UBERON:0002345	60.46	gold quality
thoracic aorta	UBERON:0001515	60.08	gold quality
prefrontal cortex	UBERON:0000451	60.04	gold quality
ascending aorta	UBERON:0001496	59.87	gold quality
right adrenal gland	UBERON:0001233	58.03	gold quality
left adrenal gland cortex	UBERON:0035825	57.80	gold quality
left adrenal gland	UBERON:0001234	57.65	gold quality
adrenal gland	UBERON:0002369	57.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.