ITPKB-IT1

Summary

ITPKB-IT1 (ITPKB intronic transcript 1, HGNC:41349) is a long non-coding RNA gene on chromosome 1q42.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41349
Approved symbol	ITPKB-IT1
Name	ITPKB intronic transcript 1
Location	1q42.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228382
Ensembl biotype	lncRNA
Entrez	100506443
RNAcentral	URS000075BD1A — lncRNA, 1347 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000412918, ENST00000443422, ENST00000729972

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412918 — 2 exons

Exon	Start	End
ENSE00004058098	226656079	226657274
ENSE00004058100	226674917	226675111

Expression profiles

Bgee: expression breadth ubiquitous, 165 present calls, max score 90.46.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1211 / max 217.0966, expressed in 294 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
17765	1.1211	294

Top tissues by expression

208 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
vena cava	UBERON:0004087	90.46	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.01	gold quality
cerebellar vermis	UBERON:0004720	87.70	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	86.75	silver quality
body of tongue	UBERON:0011876	85.75	silver quality
substantia nigra pars compacta	UBERON:0001965	85.72	silver quality
pons	UBERON:0000988	85.16	gold quality
lateral nuclear group of thalamus	UBERON:0002736	85.12	gold quality
subthalamic nucleus	UBERON:0001906	85.03	silver quality
substantia nigra pars reticulata	UBERON:0001966	84.49	silver quality
dorsal plus ventral thalamus	UBERON:0001897	84.46	silver quality
ventral tegmental area	UBERON:0002691	84.00	silver quality
pharyngeal mucosa	UBERON:0000355	83.76	silver quality
pericardium	UBERON:0002407	83.46	gold quality
tongue	UBERON:0001723	83.42	silver quality
inferior vagus X ganglion	UBERON:0005363	83.39	silver quality
kidney epithelium	UBERON:0004819	82.92	silver quality
cardia of stomach	UBERON:0001162	82.55	silver quality
superior surface of tongue	UBERON:0007371	82.10	silver quality
pylorus	UBERON:0001166	81.98	silver quality
medulla oblongata	UBERON:0001896	81.92	silver quality
superior vestibular nucleus	UBERON:0007227	81.69	silver quality
trachea	UBERON:0003126	81.58	silver quality
saphenous vein	UBERON:0007318	81.40	silver quality
renal medulla	UBERON:0000362	80.47	silver quality
nipple	UBERON:0002030	80.45	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	79.51	silver quality
trigeminal ganglion	UBERON:0001675	79.30	silver quality
pancreatic ductal cell	CL:0002079	79.29	silver quality
synovial joint	UBERON:0002217	78.79	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.