JARID2-AS1

Summary

JARID2-AS1 (JARID2 antisense RNA 1, HGNC:40314) is a long non-coding RNA gene on chromosome 6p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40314
Approved symbol	JARID2-AS1
Name	JARID2 antisense RNA 1
Location	6p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235488
Ensembl biotype	lncRNA
Entrez	100506681
RNAcentral	URS000075B301 — lncRNA, 517 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000441978

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441978 — 2 exons

Exon	Start	End
ENSE00001613975	15248510	15248634
ENSE00001728738	15247815	15248144

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 93.96.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7323 / max 41.6971, expressed in 283 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
71923	0.6909	271
71924	0.0413	14

Top tissues by expression

252 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	93.96	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.74	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.72	gold quality
left testis	UBERON:0004533	91.37	gold quality
right testis	UBERON:0004534	90.79	gold quality
testis	UBERON:0000473	87.96	gold quality
buccal mucosa cell	CL:0002336	81.34	gold quality
sural nerve	UBERON:0015488	78.35	gold quality
bone marrow cell	CL:0002092	75.26	gold quality
granulocyte	CL:0000094	74.49	gold quality
monocyte	CL:0000576	73.15	gold quality
leukocyte	CL:0000738	72.58	gold quality
adult organism	UBERON:0007023	71.26	gold quality
colonic epithelium	UBERON:0000397	67.10	silver quality
cortical plate	UBERON:0005343	66.54	gold quality
blood	UBERON:0000178	64.36	gold quality
stromal cell of endometrium	CL:0002255	61.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.20	gold quality
gastrocnemius	UBERON:0001388	59.87	gold quality
muscle of leg	UBERON:0001383	59.84	gold quality
adrenal tissue	UBERON:0018303	58.89	gold quality
right lung	UBERON:0002167	58.43	gold quality
tibialis anterior	UBERON:0001385	58.10	silver quality
prefrontal cortex	UBERON:0000451	57.40	gold quality
bone marrow	UBERON:0002371	57.18	gold quality
islet of Langerhans	UBERON:0000006	57.03	gold quality
pancreatic ductal cell	CL:0002079	56.80	silver quality
adenohypophysis	UBERON:0002196	56.27	gold quality
ileal mucosa	UBERON:0000331	56.06	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.71

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Autoregulation of JARID2 through PRC2 interaction with its antisense ncRNA. (PMID:33126912)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.