JRKL-AS1

Summary

JRKL-AS1 (JRKL antisense RNA 1, HGNC:43670) is a long non-coding RNA gene on chromosome 11q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43670
Approved symbol	JRKL-AS1
Name	JRKL antisense RNA 1
Location	11q21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255679
Ensembl biotype	lncRNA
Entrez	100874053
RNAcentral	URS0000D5A512 — lncRNA, 648 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000511243, ENST00000835074, ENST00000835075, ENST00000835076, ENST00000835077, ENST00000835078, ENST00000835079, ENST00000835080

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511243 — 4 exons

Exon	Start	End
ENSE00002087711	96449932	96450033
ENSE00002211478	96506729	96506826
ENSE00002232344	96447132	96447243
ENSE00002268995	96447349	96447462

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 87.32.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0094 / max 4.9619, expressed in 6 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
121923	0.0094	6

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.32	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.39	gold quality
ventricular zone	UBERON:0003053	69.21	gold quality
skeletal muscle tissue	UBERON:0001134	69.17	gold quality
ganglionic eminence	UBERON:0004023	69.11	gold quality
left testis	UBERON:0004533	68.39	gold quality
testis	UBERON:0000473	67.99	gold quality
right testis	UBERON:0004534	67.76	gold quality
cerebellar hemisphere	UBERON:0002245	66.32	gold quality
cerebellar cortex	UBERON:0002129	66.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	65.17	gold quality
muscle tissue	UBERON:0002385	64.89	gold quality
sural nerve	UBERON:0015488	64.43	silver quality
Brodmann (1909) area 9	UBERON:0013540	62.06	gold quality
muscle of leg	UBERON:0001383	60.93	gold quality
bone marrow	UBERON:0002371	59.90	gold quality
gastrocnemius	UBERON:0001388	59.63	gold quality
mucosa of transverse colon	UBERON:0004991	59.34	gold quality
smooth muscle tissue	UBERON:0001135	59.07	gold quality
vermiform appendix	UBERON:0001154	58.76	gold quality
primary visual cortex	UBERON:0002436	58.46	gold quality
endometrium	UBERON:0001295	58.44	gold quality
lymph node	UBERON:0000029	57.84	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	57.64	gold quality
calcaneal tendon	UBERON:0003701	57.56	gold quality
islet of Langerhans	UBERON:0000006	57.37	gold quality
monocyte	CL:0000576	57.33	gold quality
brain	UBERON:0000955	57.00	gold quality
gall bladder	UBERON:0002110	56.78	gold quality
urinary bladder	UBERON:0001255	56.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.