KAAG1

Summary

KAAG1 (kidney associated DCDC2 antisense RNA 1, HGNC:21031) is a long non-coding RNA gene on chromosome 6p22.3.

Predicted to be involved in immune response.

Source: NCBI Gene 353219 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:21031
Approved symbol	KAAG1
Name	kidney associated DCDC2 antisense RNA 1
Location	6p22.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	RU2, RU2AS
Ensembl gene	ENSG00000146049
Ensembl biotype	lncRNA
OMIM	608211
Entrez	353219
RNAcentral	URS00025E34DA — lncRNA, 1383 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000274766

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000274766 — 1 exons

Exon	Start	End
ENSE00000973635	24356903	24358285

Expression profiles

Bgee: expression breadth broad, 40 present calls, max score 88.23.

Top tissues by expression

221 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.23	gold quality
buccal mucosa cell	CL:0002336	63.34	gold quality
metanephros cortex	UBERON:0010533	61.95	gold quality
cerebellar vermis	UBERON:0004720	59.99	gold quality
adult mammalian kidney	UBERON:0000082	59.79	gold quality
cortex of kidney	UBERON:0001225	57.76	gold quality
mucosa of paranasal sinus	UBERON:0005030	57.65	gold quality
kidney	UBERON:0002113	56.16	gold quality
sperm	CL:0000019	56.04	gold quality
metanephros	UBERON:0000081	55.55	gold quality
epithelium of nasopharynx	UBERON:0001951	53.42	gold quality
islet of Langerhans	UBERON:0000006	51.88	gold quality
pancreas	UBERON:0001264	50.51	gold quality
bone marrow cell	CL:0002092	49.80	gold quality
mucosa of transverse colon	UBERON:0004991	48.42	gold quality
body of pancreas	UBERON:0001150	48.22	gold quality
mammalian vulva	UBERON:0000997	47.18	gold quality
right lobe of liver	UBERON:0001114	46.59	gold quality
endometrium	UBERON:0001295	45.84	gold quality
synovial joint	UBERON:0002217	44.89	gold quality
amniotic fluid	UBERON:0000173	44.32	gold quality
liver	UBERON:0002107	43.90	gold quality
gingiva	UBERON:0001828	43.66	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
Brodmann (1909) area 23	UBERON:0013554	43.35	gold quality
nipple	UBERON:0002030	43.29	gold quality
right uterine tube	UBERON:0001302	43.26	silver quality
lower lobe of lung	UBERON:0008949	43.14	silver quality
heart right ventricle	UBERON:0002080	42.61	gold quality
secondary oocyte	CL:0000655	42.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.