KANSL1-AS1

Summary

KANSL1-AS1 (KANSL1 antisense RNA 1, HGNC:43740) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43740
Approved symbol	KANSL1-AS1
Name	KANSL1 antisense RNA 1
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000214401
Ensembl biotype	lncRNA
Entrez	644246
RNAcentral	URS000075ED2D — lncRNA, 538 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000398275, ENST00000572634, ENST00000572973, ENST00000686301

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000398275 — 2 exons

Exon	Start	End
ENSE00004139535	46193552	46193738
ENSE00004139536	46196368	46196726

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 90.93.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.9393 / max 150.2969, expressed in 1590 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
161322	5.9393	1590

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.93	gold quality
right coronary artery	UBERON:0001625	89.28	gold quality
granulocyte	CL:0000094	88.89	gold quality
apex of heart	UBERON:0002098	86.75	gold quality
gastrocnemius	UBERON:0001388	86.58	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.15	gold quality
muscle of leg	UBERON:0001383	86.15	gold quality
right uterine tube	UBERON:0001302	84.81	gold quality
fundus of stomach	UBERON:0001160	84.22	gold quality
skeletal muscle tissue	UBERON:0001134	84.05	gold quality
hindlimb stylopod muscle	UBERON:0004252	84.05	gold quality
right lobe of liver	UBERON:0001114	83.92	gold quality
body of pancreas	UBERON:0001150	83.10	gold quality
leukocyte	CL:0000738	82.73	gold quality
descending thoracic aorta	UBERON:0002345	82.70	gold quality
muscle tissue	UBERON:0002385	82.19	gold quality
blood	UBERON:0000178	82.15	gold quality
heart left ventricle	UBERON:0002084	81.78	gold quality
monocyte	CL:0000576	81.69	gold quality
lower esophagus muscularis layer	UBERON:0035833	81.57	gold quality
amygdala	UBERON:0001876	81.55	gold quality
lower esophagus	UBERON:0013473	81.49	gold quality
temporal lobe	UBERON:0001871	81.21	gold quality
subcutaneous adipose tissue	UBERON:0002190	81.02	gold quality
liver	UBERON:0002107	80.98	gold quality
tibial artery	UBERON:0007610	80.88	gold quality
popliteal artery	UBERON:0002250	80.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	80.78	gold quality
bone marrow cell	CL:0002092	80.72	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	80.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.