KAZN-AS1

Summary

KAZN-AS1 (KAZN antisense RNA 1, HGNC:53610) is a long non-coding RNA gene on chromosome 1p36.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53610
Approved symbol	KAZN-AS1
Name	KAZN antisense RNA 1
Location	1p36.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000447908
Ensembl gene	ENSG00000234593
Ensembl biotype	lncRNA
Entrez	105376762
RNAcentral	URS0000BC44CB — lncRNA, 1247 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000447908, ENST00000657979, ENST00000661309, ENST00000661613, ENST00000665002, ENST00000666654, ENST00000670776, ENST00000849106

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447908 — 5 exons

Exon	Start	End
ENSE00001701137	14350869	14351025
ENSE00001795958	14348956	14349378
ENSE00003852770	14419494	14419589
ENSE00003867571	14391445	14391578
ENSE00003881938	14390686	14390744

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 86.46.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 1.1546 / max 105.5654, expressed in 86 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10429	1.1546	86

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.46	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.16	gold quality
skeletal muscle tissue	UBERON:0001134	72.33	gold quality
bone marrow cell	CL:0002092	63.75	silver quality
colonic epithelium	UBERON:0000397	63.47	silver quality
sural nerve	UBERON:0015488	63.08	silver quality
calcaneal tendon	UBERON:0003701	62.84	gold quality
corpus callosum	UBERON:0002336	62.81	gold quality
myometrium	UBERON:0001296	60.48	gold quality
testis	UBERON:0000473	57.56	gold quality
cortical plate	UBERON:0005343	57.20	gold quality
right testis	UBERON:0004534	56.57	gold quality
left testis	UBERON:0004533	56.43	gold quality
pancreas	UBERON:0001264	56.29	gold quality
tonsil	UBERON:0002372	55.10	silver quality
leukocyte	CL:0000738	54.53	gold quality
monocyte	CL:0000576	53.78	gold quality
primary visual cortex	UBERON:0002436	53.67	gold quality
blood	UBERON:0000178	52.81	gold quality
kidney	UBERON:0002113	52.36	gold quality
urinary bladder	UBERON:0001255	51.94	gold quality
superior frontal gyrus	UBERON:0002661	51.49	gold quality
muscle of leg	UBERON:0001383	51.09	gold quality
thoracic mammary gland	UBERON:0005200	50.53	gold quality
uterine cervix	UBERON:0000002	50.41	gold quality
lymph node	UBERON:0000029	50.39	silver quality
islet of Langerhans	UBERON:0000006	49.64	gold quality
prostate gland	UBERON:0002367	49.58	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	49.26	gold quality
cortex of kidney	UBERON:0001225	48.38	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.72

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.